SCHEMBL28190832

SCHEMBL28190832

NOS(=O)(=O)c1ccc([N+](=O)[O-])cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 11/20 0.61
CA2 P00918 11/20 0.61
CA9 Q16790 8/20 0.61
CA12 O43570 6/20 0.61
CA14 Q9ULX7 5/20 0.61
CA7 P43166 4/20 0.61
CA5A P35218 4/20 0.61
CA3 P07451 3/20 0.61
CA4 P22748 3/20 0.61
CA6 P23280 3/20 0.61
CA13 Q8N1Q1 3/20 0.61
CA5B Q9Y2D0 3/20 0.61
F2 P00734 3/20 0.51
PRSS1 P07477 3/20 0.51
PRSS2 P07478 3/20 0.51
PRSS3 P35030 3/20 0.51
IDO1 P14902 2/20 0.50
ALDH1A1 P00352 2/20 0.50
MMP1 P03956 1/20 0.50
MMP2 P08253 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29488753 0.83 CA2 (0.59) CA1CA2CA9CA12CA14
SCHEMBL997443 0.83 CA2 (0.59) CA1CA2CA9CA12CA14
SCHEMBL9180970 0.82 ALDH1A1 (0.40) CA1CA2CA9CA12CA14
SCHEMBL1964478 0.79 CA2 (0.55) CA1CA2CA9CA12CA14
SCHEMBL29392071 0.79 CA2 (0.55) CA1CA2CA9CA12CA14
SCHEMBL468315 0.79 CA1 (0.55) CA1CA2CA9CA12CA14
SCHEMBL1759354 0.79 CA2 (0.55) CA1CA2CA9CA12CA14
SCHEMBL29657456 0.79 CA2 (0.55) CA1CA2CA9CA12CA14
SCHEMBL29965676 0.79 CA2 (0.55) CA1CA2CA9CA12CA14
SCHEMBL30185020 0.79 CA1 (0.55) CA1CA2CA9CA12CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107406484-A The method of acylated cyclic peptide 中化帝斯曼制药有限公司荷兰公司 2017-11-28 CN disclosed