Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.88 |
| ▸ | BLM | P54132 | 2/20 | 0.88 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.88 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.88 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.88 |
| ▸ | LMNA | P02545 | 1/20 | 0.88 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.88 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.88 |
| ▸ | TSHR | P16473 | 1/20 | 0.88 |
| ▸ | DRD1 | P21728 | 1/20 | 0.88 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.88 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.88 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.88 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.88 |
| ▸ | DRD3 | P35462 | 1/20 | 0.88 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.88 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.88 |
| ▸ | EYA2 | O00167 | 1/20 | 0.82 |
| ▸ | APP | P05067 | 1/20 | 0.82 |
| ▸ | ACE | P12821 | 1/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Edetic Acid SCHEMBL531145 | 0.97 | TDP1 (0.88) | TDP1BLMPMP22KDM4EALOX15 | |
| Edetic Acid SCHEMBL42175 | 0.97 | TDP1 (0.88) | TDP1BLMPMP22KDM4EALOX15 | |
| Edetic Acid SCHEMBL769944 | 0.97 | TDP1 (0.88) | TDP1BLMPMP22KDM4EALOX15 | |
| Pentetic Acid SCHEMBL9130818 | 0.97 | TDP1 (0.94) | TDP1BLMPMP22KDM4EALOX15 | |
| Edetic Acid SCHEMBL531146 | 0.97 | TDP1 (0.88) | TDP1BLMPMP22KDM4EALOX15 | |
| Pentetic Acid SCHEMBL456025 | 0.97 | TDP1 (0.94) | TDP1BLMPMP22KDM4EALOX15 | |
| Edetic Acid SCHEMBL4533309 | 0.97 | TDP1 (0.88) | TDP1BLMPMP22KDM4EALOX15 | |
| Edetic Acid SCHEMBL1566615 | 0.97 | TDP1 (0.88) | TDP1BLMPMP22KDM4EALOX15 | |
| Edetic Acid SCHEMBL121502 | 0.97 | TDP1 (0.88) | TDP1BLMPMP22KDM4EALOX15 | |
| Pentetic Acid SCHEMBL18917020 | 0.94 | TDP1 (0.88) | TDP1BLMPMP22KDM4EALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2148836-B1 | METHOD FOR THE PREPARATION OF REACTIVE [18]F FLUORIDE | TRASIS S A (BE) | 2017-10-25 | — | — | EP | claimed |
| US-8641903-B2 | Method for the preparation of reactive [18] F fluoride | TRASIS S.A. (BE) | 2014-02-04 | — | — | US | claimed |
| US-20100243972-A1 | METHOD FOR THE PREPARATION OF REACTIVE [18] F FLUORIDE | TRASIS S.A. (BE) | 2010-09-30 | — | — | US | claimed |
| EP-2148836-A1 | METHOD FOR THE PREPARATION OF REACTIVE Ý18¨F FLUORIDE | Universite de Liege (BE) | 2010-02-03 | — | — | EP | claimed |
| EP-1990310-A1 | Method for the preparation of reactive 18F fluoride, and for the labeling of radiotracers, using a modified non-ionic solid support and without any evaporation step | Trasis S.A. (BE) | 2008-11-12 | — | — | EP | claimed |
| WO-2008128306-A1 | METHOD FOR THE PREPARATION OF REACTIVE [18] F FLUORIDE | TRASIS S.A. (BE) | 2008-10-30 | — | — | WO | claimed |
| US-11384106-B2 | Metal tricarbonyl complexes comprising substituted iminodiactic acid ligands and uses as radioisotope tracers | EMORY UNIVERSITY (US) | 2022-07-12 | — | — | US | disclosed |
| US-20200231615-A1 | Metal Tricarbonyl Complexes Comprising Substituted Iminodiactic Acid Ligands and Uses as Radioisotope Tracers | UNIV EMORY (US) | 2020-07-23 | — | — | US | disclosed |
| US-10633404-B2 | Metal tricarbonyl complexes comprising substituted iminodiactic acid ligands and uses as radioisotope tracers | EMORY UNIVERSITY (US) | 2020-04-28 | — | — | US | disclosed |
| US-10434195-B2 | Methylsulfonamide derivatives and uses related thereto | EMORY UNIVERSITY (US) | 2019-10-08 | — | — | US | disclosed |
| US-20180057517-A1 | Metal Tricarbonyl Complexes Comprising Substituted Iminodiactic Acid Ligands and Uses as Radioisotope Tracers | UNIV EMORY (US) | 2018-03-01 | — | — | US | disclosed |
| EP-2148836-B1 | METHOD FOR THE PREPARATION OF REACTIVE [18]F FLUORIDE | TRASIS S A (BE) | 2017-10-25 | — | — | EP | disclosed |
| US-8641903-B2 | Method for the preparation of reactive [18] F fluoride | TRASIS S.A. (BE) | 2014-02-04 | — | — | US | disclosed |
| WO-2008128306-A1 | METHOD FOR THE PREPARATION OF REACTIVE [18] F FLUORIDE | TRASIS S.A. (BE) | 2008-10-30 | — | — | WO | disclosed |
| US-6022966-A | CONJUGATE COMPRISES A DOTA CHELATE COMPONENT, A BIOTIN COMPONENT AND A LINKER COMPONENT RESISTANT TO BIOTINIDASE CLEAVAGE | NEORX CORPORATION (US) | 2000-02-08 | — | — | US | disclosed |
| EP-0736035-A4 | PRETARGETING METHODS AND COMPOUNDS | NEORX CORP (US) | 1999-09-01 | — | — | EP | disclosed |
| US-5847121-A | Production of nitro-benzyl-dota via direct peptide cyclization | NEORX CORPORATION (US) | 1998-12-08 | — | — | US | disclosed |
| EP-0736035-A1 | PRETARGETING METHODS AND COMPOUNDS | NEORX CORPORATION (US) | 1996-10-09 | — | — | EP | disclosed |
| US-5541287-A | DIAGNOSIS USING CYCLIC TRIPEPTIDES WITH NITROBENZYL 1,4,7,10-TETRAAZACYCLODODECANE-N,N*,N**,N***TETRAACETIC ACID BIOTIN CONJUGATE FORMED BY ALKYLATION AND MULTISTAGE PROCESS | NEORX CORPORATION (US) | 1996-07-30 | — | — | US | disclosed |
| WO-1995015335-A2 | PRETARGETING METHODS AND COMPOUNDS | NEORX CORPORATION (US) | 1995-06-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200231615-A1 | Metal Tricarbonyl Complexes Comprising Substituted Iminodiactic Acid Ligands and Uses as Radioisotope Tracers | SLC16A8, S100A8, FGF23 | TDP1 4416/4885BLM 2066/4885PMP22 2847/4885 |
| US-20180057517-A1 | Metal Tricarbonyl Complexes Comprising Substituted Iminodiactic Acid Ligands and Uses as Radioisotope Tracers | SLC16A8, S100A8, FGF23 | TDP1 4416/4885BLM 2066/4885PMP22 2847/4885 |
| US-10434195-B2 | Methylsulfonamide derivatives and uses related thereto | CXCR4, CXCL12, CXCR2 | TDP1 2182/4885BLM 3641/4885PMP22 1350/4885 |
| US-10633404-B2 | Metal tricarbonyl complexes comprising substituted iminodiactic acid ligands and uses as radioisotope tracers | SLC16A8, S100A8, FGF23 | TDP1 4416/4885BLM 2066/4885PMP22 2847/4885 |
| US-11384106-B2 | Metal tricarbonyl complexes comprising substituted iminodiactic acid ligands and uses as radioisotope tracers | SLC16A8, S100A8, FGF23 | TDP1 4416/4885BLM 2066/4885PMP22 2847/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.