Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRNP | P04156 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | CMA1 | P23946 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 3/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | CCR8 | P51685 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17680958 | 0.75 | CCR1 (0.44) | MAPK1ALDH1A1CCR1CCR5CCR8 | |
| SCHEMBL25519630 | 0.70 | AURKA (0.49) | LMNACCR1CCR5CCR8 | |
| SCHEMBL17673285 | 0.69 | CES1 (0.39) | CMA1ALDH1A1 | |
| SCHEMBL6999877 | 0.68 | TDP1 (0.50) | KDM5AKDM4CKDM5BGAAKMT2A | |
| SCHEMBL4619603 | 0.66 | FERMT2 (0.49) | CCR1CCR5CCR8 | |
| SCHEMBL6672123 | 0.65 | CCR1 (0.40) | GAALMNAALDH1A1CCR1CCR5 | |
| Trifluoroacetic Acid SCHEMBL28101328 | 0.65 | SMN1; SMN2 (0.44) | PRNPRXFP1ALDH1A1 | |
| SCHEMBL4378078 | 0.63 | TLR8 (0.59) | GAAKMT2AMEN1ALDH1A1CCR1 | |
| SCHEMBL5542988 | 0.63 | CCR1 (0.48) | MAPK1KMT2AMEN1ALDH1A1CCR1 | |
| SCHEMBL7003951 | 0.63 | CCR1 (0.44) | KMT2AMEN1LMNAALDH1A1CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107531690-A | The amines of 4,5,6,7 tetrahydrochysene 1H pyrazolos [4,3 c] pyridine 3 as CBP and/or EP300 inhibitor | 基因泰克公司 | 2018-01-02 | — | — | CN | disclosed |