Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.49 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.49 |
| ▸ | PAK4 | O96013 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | LCK | P06239 | 1/20 | 0.49 |
| ▸ | FYN | P06241 | 1/20 | 0.49 |
| ▸ | CSF1R | P07333 | 1/20 | 0.49 |
| ▸ | RET | P07949 | 1/20 | 0.49 |
| ▸ | IGF1R | P08069 | 1/20 | 0.49 |
| ▸ | FLT1 | P17948 | 1/20 | 0.49 |
| ▸ | LTK | P29376 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | FLT3 | P36888 | 1/20 | 0.49 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.49 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.49 |
| ▸ | CLK2 | P49760 | 1/20 | 0.49 |
| ▸ | GSK3A | P49840 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17680958 | 0.87 | CCR1 (0.44) | AURKADAPK3JAK2MAP4K4PAK4 | |
| SCHEMBL12702866 | 0.85 | SMN1; SMN2 (0.49) | AURKADAPK3JAK2MAP4K4PAK4 | |
| SCHEMBL6672123 | 0.83 | CCR1 (0.40) | AURKADAPK3JAK2MAP4K4PAK4 | |
| SCHEMBL11967045 | 0.81 | AURKA (0.39) | AURKADAPK3JAK2MAP4K4PAK4 | |
| SCHEMBL8603000 | 0.80 | TRPA1 (0.44) | AURKADAPK3JAK2MAP4K4PAK4 | |
| SCHEMBL12545963 | 0.80 | NR4A2 (0.56) | AURKADAPK3JAK2MAP4K4PAK4 | |
| SCHEMBL20201897 | 0.80 | AURKA (0.38) | AURKADAPK3JAK2MAP4K4PAK4 | |
| SCHEMBL873159 | 0.76 | HTR1A (0.58) | CCR1CCR5CCR8LMNASMN1; SMN2 | |
| SCHEMBL14442426 | 0.74 | IRAK4 (0.41) | AURKADAPK3JAK2MAP4K4PAK4 | |
| SCHEMBL1619361 | 0.74 | OGA (0.49) | SMN1; SMN2NPC1SCN4ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086428-A2 | NOVEL MODULATORS OF THE ARYL HYDROCARBON RECEPTOR AND METHODS OF USE THEREOF | ALLIANTHERA (SUZHOU) BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-05-19 | — | — | WO | disclosed |