Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.44 |
| ▸ | TUBB | P07437 | 1/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.44 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12509817 | 0.81 | HSD17B3 (0.55) | HDAC1HDAC8HDAC6CYP1A2CYP3A4 | |
| SCHEMBL27822202 | 0.79 | PRMT5 (0.47) | SRD5A1 | |
| SCHEMBL21469180 | 0.79 | ALDH1A1 (0.47) | HDAC1HDAC8HDAC6CYP1A2CYP3A4 | |
| SCHEMBL16620084 | 0.79 | TUBB4A (0.44) | HDAC1HDAC8HDAC6CYP1A2CYP3A4 | |
| SCHEMBL23529776 | 0.78 | CYP1A2 (0.43) | HDAC1HDAC8HDAC6CYP1A2CYP3A4 | |
| SCHEMBL16620172 | 0.78 | AR (0.52) | HDAC1HDAC8HDAC6CYP1A2CYP3A4 | |
| SCHEMBL29804017 | 0.78 | CYP1A2 (0.43) | HDAC1HDAC8HDAC6CYP1A2CYP3A4 | |
| SCHEMBL28029098 | 0.77 | SRD5A1 (0.44) | SRD5A1NOTUM | |
| SCHEMBL29930872 | 0.77 | CHRM2 (0.63) | HDAC1HDAC8HDAC6NPSR1IDO1 | |
| SCHEMBL27822257 | 0.76 | ALDH1A1 (0.63) | LMNANOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107531690-A | The amines of 4,5,6,7 tetrahydrochysene 1H pyrazolos [4,3 c] pyridine 3 as CBP and/or EP300 inhibitor | 基因泰克公司 | 2018-01-02 | — | — | CN | disclosed |