Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 5/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28192659 | 0.83 | BCL2L1 (0.42) | KMT2AKDM4ELMNA | |
| SCHEMBL28132837 | 0.78 | KDM4E (0.42) | SLC6A3SLC6A4NPC1CASP3RAB9A | |
| SCHEMBL4142698 | 0.73 | KDM4E (0.47) | KMT2AMEN1GABRG2GABRB3GABRA3 | |
| SCHEMBL28192083 | 0.71 | KDM4E (0.42) | SLC6A3KMT2AGABRG2GABRB3GABRA3 | |
| SCHEMBL391606 | 0.71 | ABL1 (0.49) | SLC6A3SLC6A4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28267154 | 0.71 | CA12 (0.41) | KMT2AMEN1GABRG2GABRB3GABRA3 | |
| SCHEMBL3138823 | 0.71 | SLC6A4 (0.58) | SLC6A3SLC6A4NPC1CASP3RAB9A | |
| SCHEMBL13735938 | 0.71 | PTPN11 (0.57) | MAPT | |
| SCHEMBL23354126 | 0.70 | SLC6A3 (0.71) | SLC6A3SLC6A4NPC1CASP3RAB9A | |
| SCHEMBL2941745 | 0.70 | SLC6A3 (0.57) | SLC6A3SLC6A4NPC1CASP3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105745193-B | Antimycotic oxo-dihydro pyridine carbohydrazide derivative | 株式会社大熊制药 | 2017-12-01 | — | — | CN | disclosed |