Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4142698 | 0.80 | KDM4E (0.47) | KDM4EGAAGLABRD4CA12 | |
| SCHEMBL28132837 | 0.79 | KDM4E (0.42) | KDM4EGAAGLABRD4CA12 | |
| SCHEMBL391606 | 0.79 | ABL1 (0.49) | KDM4EGAAGLABRD4CA12 | |
| SCHEMBL25308830 | 0.77 | CA1 (0.43) | KDM4EGAAGLABRD4CA12 | |
| SCHEMBL28267154 | 0.75 | CA12 (0.41) | KDM4EGAAGLABRD4CA12 | |
| SCHEMBL8380028 | 0.72 | CA1 (0.52) | KDM4EGAAGLACA12CA1 | |
| SCHEMBL3095482 | 0.71 | TSHR (0.42) | KDM4EGAABRD4GABRA1GABRG2 | |
| SCHEMBL28192085 | 0.71 | SLC6A3 (0.50) | KDM4EGAAGLABRD4GABRA1 | |
| SCHEMBL5231392 | 0.69 | MYC (0.49) | KDM4EGAAGLABRD4CA12 | |
| SCHEMBL3048628 | 0.69 | GABRG2 (0.44) | KDM4EGAAGLABRD4CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105745193-B | Antimycotic oxo-dihydro pyridine carbohydrazide derivative | 株式会社大熊制药 | 2017-12-01 | — | — | CN | disclosed |