SCHEMBL28192538

SCHEMBL28192538

CC(C)(C)OC(=O)Nc1ccc(-c2cc(C(=O)O)no2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 8/20 0.65
HDAC6 Q9UBN7 8/20 0.65
HDAC3 O15379 6/20 0.65
HDAC10 Q969S8 5/20 0.65
HDAC2 Q92769 5/20 0.61
HDAC8 Q9BY41 5/20 0.61
HDAC4 P56524 2/20 0.60
HDAC7 Q8WUI4 2/20 0.60
HDAC11 Q96DB2 2/20 0.60
HDAC9 Q9UKV0 2/20 0.60
HDAC5 Q9UQL6 2/20 0.60
ALDH1A1 P00352 3/20 0.56
HPGD P15428 2/20 0.56
MAPT P10636 1/20 0.56
RECQL P46063 1/20 0.56
PSMB8 P28062 1/20 0.53
PTPN1 P18031 1/20 0.52
SCD O00767 1/20 0.49
HSD17B10 Q99714 1/20 0.49
CYP17A1 P05093 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28411916 0.84 ACR (0.62) HDAC1HDAC6HDAC3HDAC10HDAC2
SCHEMBL31341194 0.81 HDAC1 (0.59) HDAC1HDAC6HDAC3HDAC10HDAC2
SCHEMBL31341277 0.81 HDAC1 (0.59) HDAC1HDAC6HDAC3HDAC10HDAC2
SCHEMBL31341086 0.81 HDAC1 (0.59) HDAC1HDAC6HDAC3HDAC10HDAC2
SCHEMBL31341204 0.80 HDAC1 (0.58) HDAC1HDAC6HDAC3HDAC10HDAC2
SCHEMBL31341081 0.79 HDAC1 (0.57) HDAC1HDAC6HDAC3HDAC10HDAC2
SCHEMBL18585136 0.77 HDAC6 (1.00) HDAC1HDAC6HDAC3HDAC10HDAC2
SCHEMBL18585376 0.77 HDAC6 (1.00) HDAC1HDAC6HDAC3HDAC10HDAC2
SCHEMBL25359314 0.77 PSMB8 (0.59) HDAC1HDAC6HDAC3HDAC10HDAC2
SCHEMBL20865536 0.77 CYP17A1 (0.68) HDAC1HDAC6HDAC3HDAC10HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107474020-A A kind of organic molecule and its recognition methods to ethamine, diethylamine, triethylamine with recognition reaction 河南工程学院 2017-12-15 CN claimed
CN-107474020-B Organic small molecule with recognition effect on ethylamine, diethylamine and triethylamine and recognition method thereof 河南工程学院 2020-05-15 CN disclosed
CN-107474020-A A kind of organic molecule and its recognition methods to ethamine, diethylamine, triethylamine with recognition reaction 河南工程学院 2017-12-15 CN disclosed