Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CALCRLCHRM1CHRM2CHRM3F2RMAOAMAOBMAP2K1MAP2K2NTRK1NTRK2NTRK3OPRD1OPRK1OPRM1P2RY12PKLRSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASLC18A2SLC6A2SLC6A3TLR7TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8dacAdacBdacCfolAftsImrcAmrcBmrdApolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmB1rpmB2rpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmHrpmIrpmJrpmJ2rpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsR1rpsR2rpsSrpsTrpsUrpsZykgMykgO
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 known ✓ | Q9NYK1 | 2/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL29848087 | 1.00 | FDPS (0.41) | FDPSTLR8FNTAFNTBTLR7 | |
| Sulfuric Acid SCHEMBL27798882 | 0.94 | FDPS (0.43) | FDPSTLR8FNTAFNTBKMT2A | |
| Sulfuric Acid SCHEMBL62247 | 0.94 | FDPS (0.43) | FDPSTLR8FNTAFNTBKMT2A | |
| SCHEMBL1299808 | 0.90 | TLR8 (0.44) | FDPSTLR8FNTAFNTBTLR7 | |
| SCHEMBL1526997 | 0.90 | TLR8 (0.44) | FDPSTLR8FNTAFNTBTLR7 | |
| SCHEMBL2229133 | 0.90 | TLR8 (0.44) | FDPSTLR8FNTAFNTBTLR7 | |
| SCHEMBL4060199 | 0.90 | TLR8 (0.44) | FDPSTLR8FNTAFNTBTLR7 | |
| SCHEMBL301893 | 0.90 | TLR8 (0.44) | FDPSTLR8FNTAFNTBTLR7 | |
| SCHEMBL4067299 | 0.90 | TLR8 (0.44) | FDPSTLR8FNTAFNTBTLR7 | |
| SCHEMBL3664071 | 0.90 | TLR8 (0.44) | FDPSTLR8FNTAFNTBTLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105563930-B | A kind of preparation method of two-sided water repellent composite material | 江阴市长泾花园毛纺织有限公司 | 2018-01-09 | — | — | CN | disclosed |