Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 4/20 | 0.42 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GPR52 | Q9Y2T5 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | CHUK | O15111 | 1/20 | 0.35 |
| ▸ | PRKACA | P17612 | 1/20 | 0.35 |
| ▸ | PRKACG | P22612 | 1/20 | 0.35 |
| ▸ | PRKACB | P22694 | 1/20 | 0.35 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9696617 | 0.78 | IKBKB (0.49) | NNMTSIRT3TDP1POLBKDM4E | |
| SCHEMBL21906152 | 0.77 | POLB (0.50) | NNMTSIRT3TDP1POLBKDM4E | |
| SCHEMBL20321455 | 0.73 | BCHE (0.40) | NNMTSIRT3TDP1POLBKDM4E | |
| SCHEMBL16931060 | 0.72 | HSP90AA1 (0.42) | NNMTSIRT3TDP1POLBGPR52 | |
| SCHEMBL6748636 | 0.71 | SIRT3 (0.46) | NNMTSIRT3TDP1POLBKDM4E | |
| SCHEMBL7083041 | 0.71 | NNMT (0.50) | NNMTSIRT3TDP1POLBKDM4E | |
| SCHEMBL27707436 | 0.71 | NNMT (0.49) | NNMTSIRT3TDP1POLBKDM4E | |
| SCHEMBL28628579 | 0.70 | SMN1; SMN2 (0.62) | NNMTSIRT3TDP1POLBKDM4E | |
| SCHEMBL14197608 | 0.69 | POLB (0.41) | NNMTPOLBKDM4EGPR52SMN1; SMN2 | |
| SCHEMBL28192592 | 0.69 | PARP1 (0.37) | NNMTKDM4ESMN1; SMN2PARP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107411992-A | Make the method for keratin material decolouring using thiopyridone compound | 莱雅公司 | 2017-12-01 | — | — | CN | claimed |