Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.37 |
| ▸ | GABRP | O00591 | 2/20 | 0.37 |
| ▸ | GABRD | O14764 | 2/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.37 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.37 |
| ▸ | GABRE | P78334 | 2/20 | 0.37 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.37 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.37 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.37 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.37 |
| ▸ | EEF2K | O00418 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30761561 | 0.76 | GABRP (0.40) | PARP1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL7846286 | 0.71 | GABRP (0.42) | PARP1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL28192591 | 0.69 | NNMT (0.42) | PARP1HTTKDM4ESMN1; SMN2IKBKB | |
| SCHEMBL14554116 | 0.68 | CASP1 (0.42) | PARP1GRM1NNMT | |
| SCHEMBL16390153 | 0.68 | PSMB5 (0.47) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL25530529 | 0.66 | GABRP (0.36) | PARP1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL9695834 | 0.66 | EEF2K (0.44) | PARP1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL28012934 | 0.66 | HTT (0.41) | PARP1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL20321443 | 0.66 | EEF2K (0.44) | PARP1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL4567034 | 0.64 | MAPT (0.51) | MEN1KMT2AHTTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107411992-A | Make the method for keratin material decolouring using thiopyridone compound | 莱雅公司 | 2017-12-01 | — | — | CN | claimed |