⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ribose (Furanose) SCHEMBL7120818 | 0.78 | MAPT (0.35) | — | |
| SCHEMBL887785 | 0.77 | TSHR (0.30) | — | |
| SCHEMBL1060663 | 0.77 | TSHR (0.30) | — | |
| SCHEMBL1061098 | 0.75 | — | — | |
| SCHEMBL1059438 | 0.74 | — | — | |
| SCHEMBL8741525 | 0.74 | — | — | |
| SCHEMBL2384817 | 0.74 | — | — | |
| SCHEMBL3266280 | 0.71 | — | — | |
| SCHEMBL6036511 | 0.70 | — | — | |
| SCHEMBL1763993 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765845-B1 | STABLE CYANINE DYE PHOSPHORAMIDITES | BECKMAN COULTER INC (US) | 2010-10-27 | — | — | EP | claimed |
| US-11001605-B2 | Cyclic dinucleotides containing benzimidazole, method for the production of same, and use of same to activate stimulator of interferon genes (sting)-dependent signaling pathways | BIOLOG LIFE SCIENCE INSTITUTE GMBH & CO. KG (DE) | 2021-05-11 | — | — | US | disclosed |
| US-20200040028-A1 | CYCLIC DINUCLEOTIDES CONTAINING BENZIMIDAZOLE, METHOD FOR THE PRODUCTION OF SAME, AND USE OF SAME TO ACTIVATE STIMULATOR OF INTERFERON GENES (STING)-DEPENDENT SIGNALING PATHWAYS | BIOLOG LSI FORSCHUNGS- UND BETEILIGUNGS-GMBH (DE) | 2020-02-06 | — | — | US | disclosed |
| US-6900301-B2 | Backbone modified oligonucleotide analogues | ISIS PHARMACEUTICALS, INC. (US) | 2005-05-31 | — | — | US | disclosed |
| US-20040171564-A1 | Antisense oligonucleotide modulation of human serine/threonine protein phosphatase gene expression | HONKANEN RICHARD E (US) | 2004-09-02 | — | — | US | disclosed |
| US-6784290-B1 | FOR DIAGNOSIS, DETECTION AND TREATMENT OF CANCERS/TUMORS | ISIS PHARMACEUTICALS, INC. | 2004-08-31 | — | — | US | disclosed |
| US-20040072786-A1 | Antisense oligonucleotide inhibition of ras | MONIA BRETT P (US) | 2004-04-15 | — | — | US | disclosed |
| US-20030045705-A1 | Backbone modified oligonucleotide analogues | ISIS PHARMACEUTICALS, INC. | 2003-03-06 | — | — | US | disclosed |
| US-20030013670-A1 | Antisense oligonucleotide inhibition of ras | ISIS PHARMACEUTICALS, INC. | 2003-01-16 | — | — | US | disclosed |
| US-20020052331-A1 | Compositions and methods for antisense inhibition of protein translation | BAKER BRENDA (US) | 2002-05-02 | — | — | US | disclosed |
| EP-0586570-B1 | BACKBONE MODIFIED OLIGONUCLEOTIDE ANALOGUES | ISIS PHARMACEUTICALS INC (US) | 2000-09-13 | — | — | EP | disclosed |
| EP-1004593-A2 | Backbone modified oligonucleotide analogues | ISIS PHARMACEUTICALS, INC. (US) | 2000-05-31 | — | — | EP | disclosed |
| EP-0540742-A1 | OLIGODEOXYRIBONUCLEOTIDES | Shudo, Koichi, Prof. Dr. (JP) | 1993-05-12 | — | — | EP | disclosed |