Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1B | O75688 | 3/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | PPP1CC | P36873 | 2/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28193535 | 0.83 | PPM1B (0.41) | PPM1BPTPN1PPP1CCNFKB1LMNA | |
| SCHEMBL7470486 | 0.80 | — | — | |
| SCHEMBL18380884 | 0.80 | SMYD3 (0.47) | HSD11B1DRD2NFKB1NFKB2RELA | |
| SCHEMBL7788916 | 0.80 | SMYD3 (0.47) | HSD11B1DRD2NFKB1NFKB2RELA | |
| SCHEMBL15943756 | 0.79 | HSD11B1 (0.45) | PPM1BPTPN1PPP1CCHSD11B1DRD2 | |
| Hydrochloric Acid SCHEMBL3971132 | 0.79 | SMYD3 (0.46) | HSD11B1DRD2NFKB1NFKB2RELA | |
| SCHEMBL509424 | 0.77 | BTK (0.55) | HSD11B1DRD2NFKB1NFKB2RELA | |
| SCHEMBL471721 | 0.77 | BTK (0.55) | HSD11B1DRD2NFKB1NFKB2RELA | |
| SCHEMBL14805424 | 0.77 | BTK (0.55) | HSD11B1DRD2NFKB1NFKB2RELA | |
| SCHEMBL468432 | 0.77 | TFPI2 (0.41) | PPM1BPTPN1PPP1CCNFKB1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104211624-B | For the pleuromutilin derivative for the disease for treating microbe-mediated | 纳布里瓦治疗股份公司 | 2017-12-15 | — | — | CN | disclosed |