Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28193948 | 0.81 | KDM6B (0.31) | — | |
| SCHEMBL28296067 | 0.72 | MMP2 (0.58) | — | |
| SCHEMBL28306548 | 0.68 | SRC (0.34) | — | |
| SCHEMBL2648605 | 0.64 | — | — | |
| SCHEMBL12824634 | 0.63 | QPCT (0.32) | — | |
| SCHEMBL11983587 | 0.63 | PIM1 (0.33) | — | |
| SCHEMBL4765262 | 0.61 | HTT (0.40) | POLB | |
| SCHEMBL27960124 | 0.61 | P4HTM (0.42) | POLB | |
| SCHEMBL27960128 | 0.61 | ESR1 (0.32) | POLB | |
| SCHEMBL11983451 | 0.61 | GLA (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107531714-A | Imidazopyrazines ketone as PDE1 inhibitor | H.隆德贝克有限公司 | 2018-01-02 | — | — | CN | disclosed |