Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | BRS3 | P32247 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28307566 | 0.85 | SRC (0.33) | SRCBRS3 | |
| SCHEMBL14151491 | 0.78 | HRH3 (0.31) | SRC | |
| SCHEMBL28193442 | 0.68 | POLB (0.30) | — | |
| SCHEMBL28262433 | 0.68 | GPR84 (0.49) | — | |
| SCHEMBL28296067 | 0.67 | MMP2 (0.58) | SRCMMP2 | |
| SCHEMBL21657842 | 0.65 | POLB (0.49) | SRC | |
| SCHEMBL28269116 | 0.65 | ADRA2C (0.47) | — | |
| SCHEMBL12824634 | 0.63 | QPCT (0.32) | — | |
| SCHEMBL8019346 | 0.59 | HRH1 (0.51) | BRS3 | |
| SCHEMBL1387583 | 0.59 | ALDH1A1 (0.42) | BRS3MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107531714-B | Imidazopyrazines ketone as PDE1 inhibitor | H.隆德贝克有限公司 | 2019-07-19 | — | — | CN | disclosed |