Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.35 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrahydrofuran SCHEMBL27268317 | 0.84 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2PKMTP53MEN1 | |
| Lactic Acid SCHEMBL28729308 | 0.82 | TP53 (0.58) | ALDH1A1SMN1; SMN2PKMTP53CYP1A2 | |
| Lactic Acid SCHEMBL29209442 | 0.80 | TP53 (0.55) | ALDH1A1SMN1; SMN2PKMTP53CYP1A2 | |
| SCHEMBL2128694 | 0.78 | — | — | |
| SCHEMBL946721 | 0.78 | TDP1 (0.53) | ALDH1A1RNPEPTDP1HPGDHSD17B10 | |
| SCHEMBL12149426 | 0.78 | — | — | |
| SCHEMBL15864 | 0.78 | — | — | |
| Tetrahydrofuran SCHEMBL28650393 | 0.75 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2PKMHSD17B10LMNA | |
| Tetrahydrofuran SCHEMBL1704980 | 0.75 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2PKMHSD17B10LMNA | |
| Tetrahydrofuran SCHEMBL44945 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104910391-B | A kind of biodegradable hydrogel with bioactivity and preparation method thereof | 武汉理工大学 | 2017-12-05 | — | — | CN | disclosed |