Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.66 |
| ▸ | MAOB | P27338 | 4/20 | 0.66 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.66 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | ECE1 | P42892 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chromone SCHEMBL27978219 | 0.83 | MAOA (0.95) | MAOAMAOBFTOCA1CA9 | |
| Chromone SCHEMBL28327088 | 0.83 | MAOA (0.95) | MAOAMAOBFTOCA1CA9 | |
| Chromone SCHEMBL3710911 | 0.82 | MAOA (0.58) | MAOAMAOBFTOACHEGRM5 | |
| Chromone SCHEMBL28268880 | 0.81 | MAOA (1.00) | MAOAMAOBFTOCA1CA9 | |
| Chromone SCHEMBL29369932 | 0.81 | MAOA (1.00) | MAOAMAOBFTOCA1CA9 | |
| Chromone SCHEMBL6347379 | 0.81 | MAOA (1.00) | MAOAMAOBFTOCA1CA9 | |
| Chromone SCHEMBL30075941 | 0.81 | MAOA (1.00) | MAOAMAOBFTOCA1CA9 | |
| Chromone SCHEMBL37994 | 0.81 | MAOA (1.00) | MAOAMAOBFTOCA1CA9 | |
| Benzofuran SCHEMBL29213064 | 0.81 | CA1 (0.44) | MAOAMAOBFTOCA1CA9 | |
| Chromone SCHEMBL31277121 | 0.79 | MAOA (0.95) | MAOAMAOBFTOCA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107556296-B | 2-hydroxy-3-azacyclo chromone compound, synthetic method thereof and application thereof in antifungal drugs | 南京工业大学 | 2020-10-02 | — | — | CN | disclosed |
| CN-107556296-A | 2-hydroxy-3-azacyclo chromone compound, synthetic method thereof and application thereof in antifungal drugs | 南京工业大学 | 2018-01-09 | — | — | CN | disclosed |