Chromone

Chromone

SCHEMBL37994

O=c1ccoc2ccccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 6/20 1.00
MAOB P27338 6/20 1.00
FTO Q9C0B1 2/20 1.00
ACHE P22303 1/20 0.53
GRM5 P41594 1/20 0.53
KDM4E B2RXH2 2/20 0.48
DAO P14920 1/20 0.45
HPGD P15428 3/20 0.44
ALDH1A1 P00352 2/20 0.44
CYP3A4 P08684 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
GLA P06280 1/20 0.44
MAPT P10636 1/20 0.44
PGAM1 P18669 1/20 0.44
CASP1 P29466 1/20 0.44
CASP7 P55210 1/20 0.44
HSD17B10 Q99714 1/20 0.44
MEN1 O00255 1/20 0.44
LMNA P02545 1/20 0.44
KMT2A Q03164 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chromone SCHEMBL28268880 1.00 MAOA (1.00) MAOAMAOBFTOACHEGRM5
Chromone SCHEMBL29369932 1.00 MAOA (1.00) MAOAMAOBFTOACHEGRM5
Chromone SCHEMBL30075941 1.00 MAOA (1.00) MAOAMAOBFTOACHEGRM5
Chromone SCHEMBL6347379 1.00 MAOA (1.00) MAOAMAOBFTOACHEGRM5
Chromone SCHEMBL31277121 0.98 MAOA (0.95) MAOAMAOBFTOACHEGRM5
Chromone SCHEMBL1034108 0.98 MAOA (0.95) MAOAMAOBFTOACHEGRM5
Chromone SCHEMBL3203755 0.98 MAOA (0.95) MAOAMAOBFTOACHEGRM5
Chromone SCHEMBL30865752 0.98 MAOA (0.95) MAOAMAOBFTOACHEGRM5
Chromone SCHEMBL31622445 0.98 MAOA (0.95) MAOAMAOBFTOACHEGRM5
Chromone SCHEMBL29374821 0.98 MAOA (0.95) MAOAMAOBFTOACHEGRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 14101 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747245-A1 PHARMACEUTICAL COMPOUNDS Almac Discovery Limited (GB) 2026-05-27 EP claimed
US-12636251-B1 Glycoside-containing aqueous formulations having a lipophilic active component Doane Technology Group LLC (US) 2026-05-26 US claimed
CN-122059625-A Mineral wool binder 洛科威有限公司 2026-05-19 CN claimed
CN-122036668-A Alpha, beta unsaturated ketone substituted chromone derivative and medicinal use thereof 中国药科大学 2026-05-15 CN claimed
CN-122005748-A Composition containing agilawood extract and preparation method and application thereof 北京奕德堂科技有限公司 2026-05-12 CN claimed
EP-4731727-A1 HALF-WAVE PLATE Merck Patent GmbH (DE) 2026-04-29 EP claimed
EP-4713413-A1 CHIRAL REACTIVE MESOGEN MIXTURE Merck Patent GmbH (DE) 2026-03-25 EP claimed
EP-4713414-A1 OPTICAL ELEMENT COMPRISING A CHIRAL LC POLYMER FILM Merck Patent GmbH (DE) 2026-03-25 EP claimed
CN-121586757-A Half wave plate 默克专利股份有限公司 2026-02-27 CN claimed
US-20260028771-A1 PROTEIN-TEXTILE/PAPER-COMPOSITES AND ARTICLES CONTAINING THE SAME UNIV CONNECTICUT (US) 2026-01-29 US claimed
US-4232012-A Composition FISONS LIMITED (GB) 1980-11-04 US claimed
US-4220645-A CARDIOVASCULAR DISORDERS THEA (THERAPEUTIQUE ET APPLICATIONS) SA (FR) 1980-09-02 US claimed
US-4189571-A Esters of cromoglycates FISONS LIMITED (GB) 1980-02-19 US claimed
US-4151292-A ANTIINFLAMMATORY SIDE EFFECT INHIBITION USING CHROMENE DERIVATIVES, GASTROINTESTINAL DISORDERS FISONS LIMITED (GB) 1979-04-24 US claimed
US-4145438-A METHOD FOR TREATMENT OF ECZEMA OR PSORIASIS FISONS LIMITED (GB) 1979-03-20 US claimed
US-4133889-A ANAPHYLAXIS ANTAGONISTS FISONS, LTD. (GB) 1979-01-09 US claimed
US-4105781-A ANTIALLERGENS FOR TREATMENT OF ASTHMA FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1978-08-08 US claimed
US-4049664-A ANTIALLERGENS, ANTIASTHMATICS FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1977-09-20 US claimed
US-3965122-A ANTIALLERGENS FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1976-06-22 US claimed
US-3931026-A ELECTRICALLY INSULATING ENCAPSULATING COMPOSITION FOR SEMICONDUCTOR DEVICES SEMIKRON GESELLSCHAFT FUR GLEICHRICHTERBAU UND ELEKTRONIK M.B.H. (DT) 1976-01-06 US claimed