SCHEMBL28196381

SCHEMBL28196381

C=Cc1ccc(-c2ccccc2)cc1.C=Cc1ccc2ccccc2c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RELA Q04206 1/20 0.52
ALDH1A1 P00352 5/20 0.48
TSHR P16473 1/20 0.48
KDM4E B2RXH2 2/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
ESR1 P03372 3/20 0.42
ESR2 Q92731 3/20 0.42
PTGS1 P23219 1/20 0.42
HSD17B1 P14061 1/20 0.40
HSD17B2 P37059 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
NQO2 P16083 2/20 0.40
PTGS2 P35354 1/20 0.40
GLA P06280 1/20 0.40
MAPT P10636 1/20 0.40
CYP1A1 P04798 1/20 0.40
CYP1B1 Q16678 1/20 0.40
HDAC2 Q92769 1/20 0.39
GRIN2D O15399 1/20 0.39
GRIN3B O60391 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31173792 0.90 ESR1 (0.52) RELAALDH1A1TSHRESR1ESR2
Styrene SCHEMBL3214387 0.90 RELA (0.63) RELAALDH1A1TSHRKDM4EL3MBTL1
Naphthalene SCHEMBL27465863 0.90 ALDH1A1 (0.59) RELAALDH1A1TSHRESR1ESR2
SCHEMBL5888428 0.88 ESR1 (0.55) RELAALDH1A1TSHRKDM4EL3MBTL1
SCHEMBL110160 0.88 RELA (0.58) RELAALDH1A1TSHRKDM4EL3MBTL1
SCHEMBL29357489 0.88 RELA (0.58) RELAALDH1A1TSHRKDM4EL3MBTL1
SCHEMBL2997515 0.88 RELA (0.58) RELAALDH1A1TSHRKDM4EL3MBTL1
Anthracene SCHEMBL28663344 0.86 RELA (0.56) RELAALDH1A1TSHRKDM4EL3MBTL1
Hydrochloric Acid SCHEMBL5493921 0.86 RELA (0.56) RELAALDH1A1TSHRKDM4EL3MBTL1
Butadiene SCHEMBL23403790 0.84 RELA (0.54) RELAALDH1A1TSHRKDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105408446-B The manufacture method of photochromic optical material 三井化学株式会社 2018-01-09 CN disclosed
CN-105431502-B Polymerizable composition for photochromic optical material 三井化学株式会社 2017-12-26 CN disclosed