SCHEMBL28196440

SCHEMBL28196440

CCCCCCCCCCCCCC(O)n1ccnc1

nearest known ligand 0.69

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 6/20 0.47
CYP17A1 P05093 3/20 0.43
TBXA2R P21731 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11593809 1.00 TBXAS1 (0.47) TBXAS1CYP17A1TBXA2R
SCHEMBL28278661 1.00 TBXAS1 (0.47) TBXAS1CYP17A1TBXA2R
SCHEMBL18045656 0.93 CYP17A1 (0.49) TBXAS1CYP17A1
SCHEMBL13949281 0.87 NFKB1 (0.39)
SCHEMBL10438413 0.85 CYP17A1 (0.46) TBXAS1CYP17A1
Thiocyanic Acid SCHEMBL28990409 0.84 CYP17A1 (0.43) TBXAS1CYP17A1
SCHEMBL9722522 0.82 TBXAS1 (0.50) TBXAS1CYP17A1TBXA2R
SCHEMBL3421199 0.82 TBXAS1 (0.50) TBXAS1CYP17A1TBXA2R
SCHEMBL3851254 0.82 TBXAS1 (0.50) TBXAS1CYP17A1TBXA2R
SCHEMBL18885407 0.82 TBXAS1 (0.50) TBXAS1CYP17A1TBXA2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107470341-A A kind of restorative procedure of heavy-metal contaminated soil 昆明理工大学 2017-12-15 CN disclosed