Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.36 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL711033 | 0.88 | LMNA (0.55) | LMNAKMT2AMEN1THRBBLM | |
| Benzene SCHEMBL28197607 | 0.86 | LMNA (0.52) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL3045043 | 0.82 | LMNA (0.48) | LMNAKMT2AMEN1THRBBLM | |
| Biphenyl SCHEMBL4457432 | 0.81 | LMNA (0.46) | LMNAKMT2AMEN1THRBBLM | |
| Toluene SCHEMBL28029835 | 0.78 | ALDH1A1 (0.45) | LMNAKMT2AMEN1THRBBLM | |
| Chlorobenzene SCHEMBL28196887 | 0.78 | KMT2A (0.43) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL3735222 | 0.78 | MEN1 (0.43) | LMNAKMT2AMEN1THRBBLM | |
| Pyridine SCHEMBL1221198 | 0.76 | KMT2A (0.41) | LMNAKMT2AMEN1THRBBLM | |
| Thiophene SCHEMBL28919214 | 0.75 | TDP1 (0.48) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL4453445 | 0.74 | MEN1 (0.39) | LMNAKMT2AMEN1THRBBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107641068-A | A kind of preparation method of indone analog derivative | 浙江工业大学 | 2018-01-30 | — | — | CN | disclosed |