Formamide

Formamide

SCHEMBL28197249

CC(C)(C)C(=O)OCCl.NC=O

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 1/20 0.37
BTN3A1 O00481 3/20 0.35
POLB P06746 1/20 0.33
GAA P10253 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
PKM P14618 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL300 0.89
Pivalate SCHEMBL9948648 0.82 PRKCA (0.39) PRKCABTN3A1POLBGAANPSR1
SCHEMBL12987662 0.74 DGAT1 (0.37) PRKCA
Butyric Acid SCHEMBL28407524 0.74 FFAR3 (0.50) PRKCAPOLBGAANPSR1
Piperidine SCHEMBL6055565 0.72 PRKCA (0.33) PRKCA
SCHEMBL11052842 0.72
SCHEMBL19788104 0.72
SCHEMBL23218023 0.71 CYP4F2 (0.55) PRKCAPKM
SCHEMBL28106792 0.71 PRKCA (0.36) PRKCA
SCHEMBL3910492 0.70 POLB (0.43) PRKCABTN3A1POLBGAANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106083858-B The preparation method of L-084 河南全宇制药股份有限公司 2018-02-06 CN disclosed