SCHEMBL28197282

SCHEMBL28197282

CCC=Cc1cc(Cl)c(Cl)c(Cl)c1

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
CYP3A4 P08684 2/20 0.33
HPGD P15428 1/20 0.33
CRHBP P24387 1/20 0.33
CRHR2 Q13324 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TYMP P19971 1/20 0.32
SIGMAR1 Q99720 2/20 0.31
TMEM97 Q5BJF2 1/20 0.31
EBP Q15125 1/20 0.31
AHR P35869 1/20 0.30
ALDH3A1 P30838 1/20 0.30
ALDH1A3 P47895 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL256044 0.79 AHR (0.48) ALDH1A1TYMPAHR
SCHEMBL256052 0.78 CHAT (0.50) ALDH1A1
SCHEMBL28412656 0.74 TSHR (0.34) ALDH1A1CYP3A4HPGDCRHBPCRHR2
SCHEMBL29371144 0.74 TRPA1 (0.48) ALDH1A1CYP3A4SIGMAR1TMEM97EBP
SCHEMBL10160933 0.74 TRPA1 (0.48) ALDH1A1CYP3A4SIGMAR1TMEM97EBP
SCHEMBL2622604 0.72 ALDH1A1 (0.45) ALDH1A1CYP3A4HPGDCRHBPCRHR2
SCHEMBL17655770 0.71 TP53 (0.44) ALDH1A1CYP3A4TYMPAHR
SCHEMBL257116 0.71 AHR (0.36) TYMPAHR
SCHEMBL13772832 0.71 AHR (0.36) TYMPAHR
SCHEMBL257120 0.71 AHR (0.36) TYMPAHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104981160-B Pesticidal compositions and methods related thereto 美国陶氏益农公司 2018-04-20 CN disclosed
CN-104981154-B Pesticidal compositions and methods related thereto 美国陶氏益农公司 2018-01-26 CN disclosed