SCHEMBL2819783

SCHEMBL2819783

CO[Si](CC(C)(C)CN)(OC)OC

nearest known ligand 0.45

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.45
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7847088 0.83
SCHEMBL57138 0.75 CYP2D6 (0.41) CYP2D6
SCHEMBL16789738 0.74
SCHEMBL730632 0.71
SCHEMBL5413240 0.71
SCHEMBL8845656 0.70
SCHEMBL12190436 0.69
SCHEMBL5421417 0.67
SCHEMBL23526595 0.67
SCHEMBL1179483 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4501303-A2 INORGANIC DENTAL FILLERS INCLUDING A SILANE TREATED SURFACE Solventum Intellectual Properties Company (US) 2025-02-05 EP disclosed
US-20200315924-A1 INORGANIC DENTAL FILLERS INCLUDING A SILANE TREATED SURFACE SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2020-10-08 US disclosed
US-8372514-B2 Moisture-curing composition comprising at least two polymers having silane groups SIKA TECHNOLOGY AG (CH) 2013-02-12 US disclosed
US-8029577-B2 Lightening and/or dyeing of human keratin fibres via a composition comprising a particular amino silicon compound and composition and device L'OREAL S.A. (FR) 2011-10-04 US disclosed
US-7909889-B2 Lightening and/or coloring human keratin fibers using at least one aminotrialkoxy silane or at least one aminotrialkenyloxy silane composition L'OREAL S.A. (FR) 2011-03-22 US disclosed
US-7905927-B2 Method for lightening and/or coloring human keratin fibers using a composition comprising an aminotrialkoxy silane or aminotrialkenyloxy silane compound and device L'OREAL, SA (FR) 2011-03-15 US disclosed
US-20100303748-A1 METHOD FOR LIGHTENING AND/OR COLORING HUMAN KERATIN FIBERS USING A COMPOSITION COMPRISING AN AMINOTRIALKOXY SILANE OR AMINOTRIALKENYLOXY SILANE COMPOUND AND DEVICE L'OREAL S.A. (FR) 2010-12-02 US disclosed
US-20100297049-A1 LIGHTENING AND/OR DYEING OF HUMAN KERATIN FIBRES BY MEANS OF A COMPOSITION COMPRISING A PARTICULAR AMINO SILICON COMPOUND AND COMPOSITION AND DEVICE L'OREAL S.A. (FR) 2010-11-25 US disclosed
US-20100275387-A1 LIGHTENING AND/OR COLORING HUMAN KERATIN FIBERS USING AT LEAST ONE AMINOTRIALKOXY SILANE OR AT LEAST ONE AMINOTRIALKENYLOXY SILANE COMPOSITION L'OREAL S.A. (FR) 2010-11-04 US disclosed
US-20100247929-A1 MOISTURE-CURING COMPOSITION COMPRISING AT LEAST TWO POLYMERS HAVING SILANE GROUPS SIKA TECHNOLOGY AG (CH) 2010-09-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100303748-A1 METHOD FOR LIGHTENING AND/OR COLORING HUMAN KERATIN FIBERS USING A COMPOSITION COMPRISING AN AMINOTRIALKOXY SILANE OR AMINOTRIALKENYLOXY SILANE COMPOUND AND DEVICE KRT18, FABP4, APMAP CYP2D6 3256/4885KDM4E 1417/4885
US-20200315924-A1 INORGANIC DENTAL FILLERS INCLUDING A SILANE TREATED SURFACE MSR1, H1-2, H1-3 CYP2D6 3923/4885KDM4E 1370/4885
US-20100275387-A1 LIGHTENING AND/OR COLORING HUMAN KERATIN FIBERS USING AT LEAST ONE AMINOTRIALKOXY SILANE OR AT LEAST ONE AMINOTRIALKENYLOXY SILANE COMPOSITION KRT18, FABP4, ALDH7A1 CYP2D6 2417/4885KDM4E 1211/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.