SCHEMBL28197837

SCHEMBL28197837

CCCCC(Cl)C(Cl)CCl

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.38
TDP1 Q9NUW8 2/20 0.38
DNM1 Q05193 2/20 0.38
ALDH1A1 P00352 4/20 0.35
SMN1; SMN2 Q16637 1/20 0.32
CYP3A4 P08684 1/20 0.32
FDPS P14324 1/20 0.32
LMNA P02545 1/20 0.32
CA2 P00918 2/20 0.31
MAPK1 P28482 1/20 0.31
OPRM1 P35372 1/20 0.31
SLC22A1 O15245 2/20 0.30
SLC22A2 O15244 1/20 0.30
CA1 P00915 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10424042 0.84 TSHR (0.35) TSHRTDP1DNM1ALDH1A1SMN1; SMN2
SCHEMBL6936947 0.82
SCHEMBL20076708 0.80 ALDH1A1 (0.40) TSHRTDP1DNM1ALDH1A1SMN1; SMN2
SCHEMBL7574483 0.79 TSHR (0.35) TSHRTDP1DNM1ALDH1A1SMN1; SMN2
SCHEMBL25428162 0.77
SCHEMBL28244728 0.77 TSHR (0.50) TSHRDNM1ALDH1A1FDPSLMNA
SCHEMBL28938919 0.76 ALDH1A1 (0.43) TSHRDNM1ALDH1A1SMN1; SMN2FDPS
SCHEMBL28728498 0.76 ALDH1A1 (0.48) TSHRDNM1ALDH1A1SMN1; SMN2CYP3A4
SCHEMBL7872144 0.74
SCHEMBL2479083 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116178198-A Preparation method of cyflufenapyr 南通泰禾化工股份有限公司 2023-05-30 CN disclosed
CN-107629005-A Polysubstituted phenylpyrazole derivatives and its production and use 王泊理 2018-01-26 CN disclosed