SCHEMBL7574483

SCHEMBL7574483

CCCCC(C)C(Cl)CCl

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.35
TDP1 Q9NUW8 2/20 0.35
DNM1 Q05193 2/20 0.35
OPRM1 P35372 1/20 0.33
CA1 P00915 2/20 0.32
ALDH1A1 P00352 4/20 0.32
CA2 P00918 2/20 0.31
SMN1; SMN2 Q16637 1/20 0.30
CYP3A4 P08684 1/20 0.30
FDPS P14324 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7869361 0.84
SCHEMBL11771588 0.80 DNM1 (0.35) TSHRTDP1DNM1OPRM1ALDH1A1
SCHEMBL28197837 0.79 TSHR (0.38) TSHRTDP1DNM1OPRM1CA1
SCHEMBL23393775 0.77 DNM1 (0.36) TSHRTDP1DNM1OPRM1ALDH1A1
SCHEMBL27648154 0.76
SCHEMBL7154822 0.76
SCHEMBL27700908 0.75 OPRM1 (0.44) TSHRDNM1OPRM1ALDH1A1FDPS
SCHEMBL4521414 0.75 OPRM1 (0.44) TSHRDNM1OPRM1ALDH1A1FDPS
SCHEMBL10424042 0.75 TSHR (0.35) TSHRTDP1DNM1ALDH1A1SMN1; SMN2
SCHEMBL3185161 0.74 DNM1 (0.47) TSHRTDP1DNM1OPRM1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1520702-B Electroluminescent irisium compounds with fluorinated phenylpyridines, phenylpyridines and phenylquinolines and device made with such compounds DU PONT 2010-05-26 CN disclosed
CN-100438123-C Electroluminescent iridium compounds containing fluorinated phenylpyridines, phenylpyrimidines, and phenylquinolines and devices made with the compounds DU PONT (US) 2008-11-26 CN disclosed
CN-1520702-A Electroluminescent irisium compounds with fluorinated phenylpyridines, phenylpyridines and phenylquinolines and device made with such compounds ��Ļ���Ű˾ 2004-08-11 CN disclosed
CN-1449640-A Electroluminescent iridium compounds with fluorinated phenylpyridines, phenylpyrimidines, and phenylquinolines and devices made with such DU PONT (US) 2003-10-15 CN disclosed
US-20020190250-A1 Electroluminescent iridium compounds with fluorinated phenylpyridines, phenylpyrimidines, and phenylquinolines and devices made with such compounds LG CHEM, LTD. (KR) 2002-12-19 US disclosed