Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 5/20 | 0.44 |
| ▸ | CA2 | P00918 | 5/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | CA3 | P07451 | 2/20 | 0.44 |
| ▸ | CA6 | P23280 | 2/20 | 0.44 |
| ▸ | CA5A | P35218 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9551766 | 0.98 | TSHR (0.50) | TSHRTP53ALDH1A1MAPTPOLB | |
| SCHEMBL9847967 | 0.91 | MAPT (0.50) | TSHRALDH1A1MAPTPOLBKMT2A | |
| SCHEMBL3035584 | 0.84 | ALDH1A1 (0.67) | TSHRTP53ALDH1A1MAPTPOLB | |
| SCHEMBL7051844 | 0.83 | CA12 (0.59) | TSHRALDH1A1MAPTPOLBKMT2A | |
| SCHEMBL1002998 | 0.81 | KMT2A (0.42) | ALDH1A1MAPTPOLBKMT2ACA1 | |
| SCHEMBL8167020 | 0.81 | ALDH1A1 (0.59) | TSHRTP53ALDH1A1MAPTPOLB | |
| SCHEMBL11856189 | 0.78 | TSHR (0.52) | TSHRTP53ALDH1A1MAPTPOLB | |
| SCHEMBL17510000 | 0.78 | CA1 (0.68) | TP53ALDH1A1MAPTKMT2ACA1 | |
| SCHEMBL3908499 | 0.77 | CYP1A2 (0.55) | TSHRALDH1A1MAPTPOLBKMT2A | |
| SCHEMBL7219677 | 0.75 | TSHR (0.60) | TSHRTP53ALDH1A1SRD5A2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108883196-A | Target the antibody-drug conjugates of GCC | 米伦纽姆医药公司 | 2018-11-23 | — | — | CN | disclosed |
| CN-108290895-A | Process for preparing cytotoxic benzodiazepine derivatives | 伊缪诺金公司 | 2018-07-17 | — | — | CN | disclosed |
| CN-107708810-A | Conjugates of cysteine engineered antibodies | 伊缪诺金公司 | 2018-02-16 | — | — | CN | disclosed |
| CN-107580604-A | Conjugate comprising cell binding agent and cytotoxic agent | 伊缪诺金公司 | 2018-01-12 | — | — | CN | disclosed |