SCHEMBL3908499

SCHEMBL3908499

NNOC(=O)c1ccncc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.55
CYP2C19 P33261 3/20 0.55
KDM4E B2RXH2 3/20 0.55
CYP3A4 P08684 2/20 0.55
CYP2D6 P10635 2/20 0.55
MPO P05164 1/20 0.55
ADORA3 P0DMS8 1/20 0.55
CYP2A6 P11509 1/20 0.55
HSD17B10 Q99714 1/20 0.53
ALDH1A1 P00352 3/20 0.48
NAPRT Q6XQN6 1/20 0.46
RAB9A P51151 3/20 0.46
NPC1 O15118 2/20 0.46
LMNA P02545 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
CYP2C9 P11712 2/20 0.46
GAA P10253 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.43
CA1 P00915 1/20 0.43
CA9 Q16790 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9847967 0.84 MAPT (0.50) CYP1A2KDM4ECYP3A4MPOALDH1A1
SCHEMBL3035584 0.78 ALDH1A1 (0.67) CYP2C19KDM4ECYP3A4HSD17B10ALDH1A1
SCHEMBL28197850 0.77 TSHR (0.52) CYP2C19ALDH1A1NAPRTSMN1; SMN2CA1
SCHEMBL7051844 0.77 CA12 (0.59) CYP1A2CYP2C19KDM4ECYP3A4CYP2D6
SCHEMBL4701603 0.76 HSD17B10 (0.50) CYP1A2CYP2C19KDM4ECYP3A4CYP2D6
Methyl Isonicotinate SCHEMBL180574 0.76 CYP1A2 (0.60) CYP1A2CYP2C19KDM4ECYP3A4CYP2D6
SCHEMBL27418916 0.76 HSD17B10 (0.59) CYP1A2CYP2C19KDM4ECYP3A4CYP2D6
Methyl Isonicotinate SCHEMBL820082 0.76 CYP1A2 (0.60) CYP1A2CYP2C19KDM4ECYP3A4CYP2D6
SCHEMBL1002998 0.75 KMT2A (0.42) KDM4EALDH1A1RAB9ANPC1SMN1; SMN2
SCHEMBL8167020 0.75 ALDH1A1 (0.59) CYP1A2KDM4EALDH1A1RAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111732537-A Preparation method of isoniazid 沈阳双鼎制药有限公司 2020-10-02 CN claimed
JP-62158488-A None JP disclosed
CN-114230514-B Method for synthesizing 3-fluoro-2-amino isonicotinic nitrile 渭南瑞联制药有限责任公司 2024-05-31 CN disclosed
CN-113227381-B Mutant strain having improved L-glutamic acid productivity and method for producing L-glutamic acid using same 大象株式会社 2024-05-24 CN disclosed
WO-2024096219-A1 MODIFIED MICROORGANISM OF GENUS CORYNEBACTERIUM WHICH PRODUCES L-GLUTAMIC ACID AND METHOD FOR PRODUCING L-GLUTAMIC ACID USING SAME 대상 주식회사 2024-05-10 WO disclosed
WO-2024096218-A1 MODIFIED MICROORGANISM OF GENUS CORYNEBACTERIUM PRODUCING L-GLUTAMIC ACID AND METHOD FOR PRODUCING L-GLUTAMIC ACID USING SAME 대상 주식회사 2024-05-10 WO disclosed
CN-117946229-A Corynebacterium variant microorganism producing L-glutamic acid and method for producing L-glutamic acid using same 大象株式会社 2024-04-30 CN disclosed
CN-117946983-A Corynebacterium variant microorganism producing L-glutamic acid and method for producing L-glutamic acid using same 大象株式会社 2024-04-30 CN disclosed
CN-115135767-B Corynebacterium glutamicum mutant strain having improved L-glutamic acid productivity and method for producing L-glutamic acid using the same 大象株式会社 2024-03-15 CN disclosed
CN-117568249-A Mutant strain having improved L-glutamic acid productivity and method for producing L-glutamic acid using same 大象株式会社 2024-02-20 CN disclosed
US-4367278-A Color photographic light-sensitive material with azopyrazolone image dyes FUJI PHOTO FILM CO., LTD. (JP) 1983-01-04 US disclosed
US-4358526-A MAGENTA AZO DYES; COLORFASTNESS FUJI PHOTO FILM CO., LTD. (JP) 1982-11-09 US disclosed
US-4309428-A Maytansinoids TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1982-01-05 US disclosed
US-4308336-A USING A HETEROCYCLIC THIOHYDROQUINONE FUJI PHOTO FILM CO., LTD. (JP) 1981-12-29 US disclosed
US-4293641-A NITROGEN CONTAINING ADDITION POLYMER AND HYDROQUINONE USED FOR COLOR SEPARATION FUJI PHOTO FILM CO., LTD. (JP) 1981-10-06 US disclosed
US-4268624-A Photographic light-sensitive sheet for the color diffusion transfer process FUJI PHOTO FILM CO., LTD. (JP) 1981-05-19 US disclosed
US-4267250-A Color diffusion transfer photographic element FUJI PHOTO FILM CO., LTD. (JP) 1981-05-12 US disclosed
US-4266013-A PHENYL OR NAPHTHYL HYDRAZIDES AS FOGGING AGENTS FUJI PHOTO FILM CO., LTD. (JP) 1981-05-05 US disclosed
EP-0025496-A1 Maytansinoids, their production and therapeutic compositions containing them Takeda Chemical Industries, Ltd. (JP) 1981-03-25 EP disclosed
US-4245028-A CONTAINING AN AZO DYE RELEASING REDOX COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1981-01-13 US disclosed