Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 10/20 | 0.50 |
| ▸ | IDH1 | O75874 | 7/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28197165 | 0.86 | IDH1 (0.48) | IDH1CNR2MRGPRX4 | |
| SCHEMBL19360379 | 0.86 | RORC (0.65) | RORCIDH1 | |
| SCHEMBL19360604 | 0.84 | IDH1 (0.47) | RORCIDH1CNR2MRGPRX4 | |
| SCHEMBL19360467 | 0.83 | RORC (0.54) | RORC | |
| SCHEMBL19360363 | 0.81 | RORC (0.65) | RORCIDH1 | |
| SCHEMBL28595332 | 0.80 | RORC (0.80) | RORC | |
| SCHEMBL28197169 | 0.80 | IDH1 (0.51) | RORCIDH1MRGPRX4 | |
| SCHEMBL19360317 | 0.79 | RORC (0.65) | RORCMRGPRX4 | |
| SCHEMBL19360378 | 0.79 | RORC (0.64) | RORCIDH1CNR2 | |
| SCHEMBL19360368 | 0.76 | RORC (0.63) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107531679-B | Aromatic amide derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2021-07-02 | — | — | CN | disclosed |
| CN-107531679-A | Aromatic amides analog derivative, its preparation method and its application in medicine | 江苏恒瑞医药股份有限公司 | 2018-01-02 | — | — | CN | disclosed |