Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 12/20 | 0.54 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19360379 | 0.86 | RORC (0.65) | RORC | |
| SCHEMBL19360586 | 0.83 | KDM4E (0.40) | RORCCYP2D6MEN1KMT2ATDP1 | |
| SCHEMBL28197905 | 0.83 | RORC (0.50) | RORC | |
| SCHEMBL19360371 | 0.79 | RORC (0.62) | RORCSLC22A12HCAR3HPGDHCAR2 | |
| SCHEMBL19360317 | 0.78 | RORC (0.65) | RORC | |
| SCHEMBL19360624 | 0.77 | L3MBTL1 (0.41) | RORCCYP2D6MEN1KMT2ATDP1 | |
| SCHEMBL19360368 | 0.75 | RORC (0.63) | RORC | |
| SCHEMBL19360300 | 0.75 | RORC (0.63) | RORC | |
| SCHEMBL7877815 | 0.74 | HCAR3 (0.47) | RORCGRIN2DGRIN2AGRIN2BGRIN2C | |
| SCHEMBL19360378 | 0.74 | RORC (0.64) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017157332-A1 | AROMATIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL APPLICATIONS THEREOF | 江苏恒瑞医药股份有限公司 | 2017-09-21 | — | — | WO | disclosed |