Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 7/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | RGS12 | O14924 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4622787 | 0.84 | CHRM3 (0.42) | CHRM3CHRM2CHRM1ESR1CHRM4 | |
| SCHEMBL3264636 | 0.84 | CHRM3 (0.42) | CHRM3CHRM2CHRM1ESR1CHRM4 | |
| SCHEMBL28197219 | 0.82 | LMNA (0.40) | CHRM3CHRM2CHRM1RIPK1KMT2A | |
| SCHEMBL5915004 | 0.80 | SMN1; SMN2 (0.43) | CHRM3CHRM2CHRM1MAPTALDH1A1 | |
| SCHEMBL5914943 | 0.80 | SMN1; SMN2 (0.43) | CHRM3CHRM2CHRM1MAPTALDH1A1 | |
| SCHEMBL12971342 | 0.76 | RIPK1 (0.40) | CHRM3CHRM2CHRM1ESR1CHRM4 | |
| SCHEMBL3389968 | 0.75 | ESR1 (0.42) | CHRM3CHRM2CHRM1ESR1CHRM4 | |
| SCHEMBL9906158 | 0.73 | ESR1 (0.41) | CHRM3CHRM2CHRM1ESR1CHRM4 | |
| SCHEMBL28671879 | 0.73 | ESR1 (0.41) | CHRM3CHRM2CHRM1ESR1CHRM4 | |
| SCHEMBL28855768 | 0.73 | ESR1 (0.41) | CHRM3CHRM2CHRM1ESR1CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107488163-A | The preparation method of (2 thienyl) 1 propyl alcohol of one kind (S) 3 N, N disubstituted amidos 1 | 天台宜生生化科技有限公司 | 2017-12-19 | — | — | CN | disclosed |