Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | DPP4 | P27487 | 6/20 | 0.44 |
| ▸ | MMP1 | P03956 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CHKA | P35790 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14602772 | 0.79 | ALDH1A1 (0.50) | DPP7ALDH1A1DPP4MMP1MMP2 | |
| SCHEMBL8612552 | 0.78 | DPP4 (0.46) | DPP7ALDH1A1DPP4MMP1MMP2 | |
| SCHEMBL5891316 | 0.78 | DPP4 (0.46) | DPP7ALDH1A1DPP4MMP1MMP2 | |
| SCHEMBL16935735 | 0.78 | DPP4 (0.46) | DPP7ALDH1A1DPP4MMP1MMP2 | |
| SCHEMBL856280 | 0.78 | DPP4 (0.46) | DPP7ALDH1A1DPP4MMP1MMP2 | |
| SCHEMBL16706638 | 0.78 | DPP4 (0.47) | DPP7ALDH1A1DPP4MMP1MMP2 | |
| Hydrochloric Acid SCHEMBL3947769 | 0.76 | DPP4 (0.45) | DPP7ALDH1A1DPP4MMP1MMP2 | |
| SCHEMBL3404386 | 0.76 | DPP7 (0.46) | DPP7ALDH1A1DPP4MMP1MMP2 | |
| SCHEMBL1539202 | 0.76 | ALDH1A1 (0.46) | DPP7ALDH1A1DPP4MMP1MMP2 | |
| SCHEMBL2768507 | 0.75 | DPP4 (0.44) | DPP7ALDH1A1DPP4MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107667106-A | 2 (base of Pyrazolopyridine 3) pyrimidine derivatives as JAK inhibitor | 阿尔米雷尔有限公司 | 2018-02-06 | — | — | CN | claimed |
| CN-107667106-A | 2 (base of Pyrazolopyridine 3) pyrimidine derivatives as JAK inhibitor | 阿尔米雷尔有限公司 | 2018-02-06 | — | — | CN | disclosed |