SCHEMBL30249695

SCHEMBL30249695

COc1cc2ncnc(Nc3cccc(O)c3)c2cc1OC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDR P35968 7/20 1.00
RET P07949 5/20 1.00
FGFR1 P11362 2/20 1.00
FLT1 P17948 2/20 1.00
EPHB2 P29323 2/20 1.00
CDK2 P24941 1/20 1.00
PIK3R1 P27986 1/20 1.00
KIF5B P33176 1/20 1.00
TTBK1 Q5TCY1 1/20 1.00
NOD1 Q9Y239 1/20 0.97
RAF1 P04049 4/20 0.77
BRAF P15056 3/20 0.77
EGFR P00533 11/20 0.77
SRC P12931 3/20 0.75
GAK O14976 2/20 0.74
RIPK2 O43353 1/20 0.74
STK10 O94804 1/20 0.74
FLT3 P36888 1/20 0.74
JAK3 P52333 1/20 0.74
AAK1 Q2M2I8 1/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29435034 1.00 KDR (1.00) KDRRETFGFR1FLT1EPHB2
SCHEMBL1180103 1.00 KDR (1.00) KDRRETFGFR1FLT1EPHB2
Hydrochloric Acid SCHEMBL30433676 0.99 NOD1 (1.00) KDRRETFGFR1FLT1EPHB2
SCHEMBL5565577 0.88 FGFR1 (0.78) KDRRETFGFR1FLT1EPHB2
SCHEMBL15052582 0.87 BRAF (1.00) KDRRETFGFR1FLT1EPHB2
SCHEMBL31060707 0.86 EGFR (1.00) KDRRETFGFR1FLT1EPHB2
SCHEMBL5482883 0.86 EGFR (1.00) KDRRETFGFR1FLT1EPHB2
SCHEMBL5474772 0.86 KDR (1.00) KDRRETFGFR1FLT1EPHB2
SCHEMBL5569018 0.86 KDR (1.00) KDRRETFGFR1FLT1EPHB2
SCHEMBL15051582 0.85 BRAF (1.00) KDRRETFGFR1FLT1EPHB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4662319-A2 PERSONALIZED CRISPR PROFILING FOR CANCER Integrate Bioscience LLC (US) 2025-12-17 EP disclosed
WO-2024189607-A1 METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR DISEASES TREATMENT DIDENKO KIRILL (MX) 2024-09-19 WO disclosed
WO-2024168301-A2 PERSONALIZED CRISPR PROFILING FOR CANCER FUNCTION ONCOLOGY, INC. (US) 2024-08-15 WO disclosed
WO-2023187599-A1 METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR THE TREATMENT OF VIRAL DISEASES DIDENKO KIRILL (MX) 2023-10-05 WO disclosed
EP-3681504-B1 METHODS OF DETECTION USING X-RAY FLUORESCENCE ICAGEN INC (US) 2023-08-23 EP disclosed
US-11573224-B2 Methods of detection using X-ray fluorescence ICAGEN, LLC (US) 2023-02-07 US disclosed