Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.50 |
| ▸ | PKM | P14618 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27906761 | 0.83 | MAPT (0.52) | MAPTPKMPOLBTDP1LMNA | |
| SCHEMBL1700061 | 0.80 | MAPT (0.47) | MAPTPKMPOLBTDP1LMNA | |
| SCHEMBL28533913 | 0.78 | MAPT (0.52) | MAPTPKMPOLBTDP1LMNA | |
| SCHEMBL28152133 | 0.78 | KMT2A (0.53) | MAPTPKMPOLBTDP1LMNA | |
| SCHEMBL28199068 | 0.78 | KMT2A (0.53) | MAPTPKMPOLBTDP1LMNA | |
| SCHEMBL28845496 | 0.78 | KMT2A (0.53) | MAPTPKMPOLBTDP1LMNA | |
| SCHEMBL16038843 | 0.78 | MAPT (0.61) | MAPTPKMPOLBTDP1LMNA | |
| SCHEMBL1699987 | 0.77 | MAPT (0.60) | MAPTPKMPOLBTDP1LMNA | |
| SCHEMBL30075005 | 0.77 | MAPT (0.60) | MAPTPKMPOLBTDP1LMNA | |
| SCHEMBL16037476 | 0.77 | MAPT (0.60) | MAPTPKMPOLBTDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108175749-A | The solid dispersions of melt extrusion containing cell death inducer | 艾伯维爱尔兰无限公司 | 2018-06-19 | — | — | CN | disclosed |
| CN-103282025-B | Melt-extruded solid dispersions containing apoptosis-inducing agents | 艾伯维爱尔兰无限公司 | 2018-01-02 | — | — | CN | disclosed |
| CN-104876927-B | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases | 艾伯维爱尔兰无限公司 | 2017-06-23 | — | — | CN | disclosed |