Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.52 |
| ▸ | PKM | P14618 | 6/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29482111 | 0.82 | MAPT (0.62) | MAPTPKMPOLBSMN1; SMN2KDM4E | |
| SCHEMBL1958872 | 0.82 | MAPT (0.62) | MAPTPKMPOLBSMN1; SMN2KDM4E | |
| SCHEMBL1699958 | 0.79 | MAPT (0.72) | MAPTPKMPOLBSMN1; SMN2KDM4E | |
| SCHEMBL30468003 | 0.79 | MAPT (0.72) | MAPTPKMPOLBSMN1; SMN2KDM4E | |
| SCHEMBL28198503 | 0.78 | MAPT (0.50) | MAPTPKMPOLBSMN1; SMN2GAA | |
| SCHEMBL29139917 | 0.78 | MAPT (0.54) | MAPTPKMPOLBSMN1; SMN2KDM4E | |
| SCHEMBL27906761 | 0.76 | MAPT (0.52) | MAPTPKMPOLBSMN1; SMN2KDM4E | |
| SCHEMBL16038843 | 0.76 | MAPT (0.61) | MAPTPKMPOLBSMN1; SMN2GAA | |
| SCHEMBL21542231 | 0.75 | MAPT (0.57) | MAPTPKMPOLBSMN1; SMN2KDM4E | |
| SCHEMBL30003577 | 0.75 | MAPT (0.55) | MAPTPKMPOLBSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112437772-A | Bcl-2 inhibitors | 百济神州有限公司 | 2021-03-02 | — | — | CN | disclosed |