SCHEMBL28198518

SCHEMBL28198518

CC1(c2cc(Cl)cc(Cl)c2)C[C]1Cl

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CCR2 P41597 1/20 0.42
TSHR P16473 2/20 0.40
SLC6A2 P23975 4/20 0.36
SLC6A3 Q01959 4/20 0.36
CHRNA1 P02708 1/20 0.36
CHRNG P07510 1/20 0.36
CHRNB1 P11230 1/20 0.36
CHRNB2 P17787 1/20 0.36
CHRNB4 P30926 1/20 0.36
CHRNA3 P32297 1/20 0.36
CHRNA4 P43681 1/20 0.36
CHRND Q07001 1/20 0.36
SLC6A4 P31645 3/20 0.33
TP53 P04637 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP11B2 P19099 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16770967 0.67 SLC6A2 (0.41) CCR2TSHRSLC6A2SLC6A3CHRNA1
SCHEMBL8210195 0.67 TSHR (0.42) CCR2TSHRSLC6A2SLC6A3CHRNA1
SCHEMBL28197918 0.65 TSHR (0.40) CCR2TSHRSLC6A2SLC6A3CHRNA1
1,3,5-Trichlorobenzene SCHEMBL429512 0.63
SCHEMBL16591245 0.62 SLC6A3 (0.37) TSHRSLC6A2SLC6A3CHRNA1CHRNG
SCHEMBL19399638 0.62 TSHR (0.42) TSHRSLC6A2SLC6A3SLC6A4TP53
SCHEMBL16884630 0.61 SLC6A2 (0.47) SLC6A2SLC6A3CHRNA1CHRNGCHRNB1
SCHEMBL20550175 0.61
1,3,5-Trichlorobenzene SCHEMBL27517345 0.61 TSHR (0.73) TSHRTP53CYP3A4
SCHEMBL17299186 0.61 OPRM1 (0.36) SLC6A2SLC6A3CHRNA1CHRNGCHRNB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107529748-A Molecule with desinsection effectiveness, and relative intermediate, composition and method 美国陶氏益农公司 2018-01-02 CN disclosed