Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 5/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 5/20 | 0.40 |
| ▸ | RELA | Q04206 | 5/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29046653 | 0.77 | BTK (0.47) | NFKB1NFKB2RELABTKGAA | |
| SCHEMBL29046655 | 0.77 | BTK (0.47) | NFKB1NFKB2RELABTKGAA | |
| SCHEMBL28199171 | 0.75 | MAPK1 (0.34) | — | |
| SCHEMBL19497263 | 0.75 | NFKB1 (0.45) | NFKB1NFKB2RELABTKGAA | |
| SCHEMBL3375342 | 0.72 | NFKB1 (0.43) | NFKB1NFKB2RELABTKGAA | |
| SCHEMBL19491081 | 0.71 | BTK (0.44) | NFKB1NFKB2RELABTKGAA | |
| SCHEMBL19491073 | 0.71 | BTK (0.44) | NFKB1NFKB2RELABTKGAA | |
| SCHEMBL16228549 | 0.71 | NFKB1 (0.40) | NFKB1NFKB2RELABTKGAA | |
| SCHEMBL28039500 | 0.69 | NFKB1 (0.40) | NFKB1NFKB2RELABTKGAA | |
| SCHEMBL28199159 | 0.69 | NFKB1 (0.40) | NFKB1NFKB2RELABTKGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105143212-B | Tripeptide epoxy ketone protease inhibitors | 欧尼斯治疗公司 | 2018-02-23 | — | — | CN | disclosed |