Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 2/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | GPR3 | P46089 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28221393 | 0.78 | NSD2 (0.38) | NSD2NOS1MAOAMEN1KMT2A | |
| SCHEMBL28287776 | 0.74 | LOX (0.33) | NSD2NOS1MEN1KMT2A | |
| SCHEMBL28312051 | 0.74 | SHMT2 (0.33) | NSD2NOS1KDM4EALDH1A1MAPT | |
| SCHEMBL28258527 | 0.73 | CCR3 (0.32) | NSD2NOS1MAPT | |
| SCHEMBL30129012 | 0.70 | SMN1; SMN2 (0.35) | MAOAMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL28176278 | 0.70 | MAPT (0.49) | MAOAKMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL32691835 | 0.69 | NOS1 (0.37) | NOS1MEN1KMT2AALDH1A1 | |
| SCHEMBL22443064 | 0.68 | KMT2A (0.46) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL14511092 | 0.68 | NSD2 (0.36) | NSD2NOS1MAOAMEN1KMT2A | |
| SCHEMBL19972843 | 0.67 | HTT (0.36) | NSD2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105555780-B | SYK inhibitors | 吉利德科学公司 | 2018-01-23 | — | — | CN | disclosed |