Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 12/20 | 0.44 |
| ▸ | MEN1 | O00255 | 11/20 | 0.44 |
| ▸ | POLB | P06746 | 9/20 | 0.44 |
| ▸ | NPC1 | O15118 | 7/20 | 0.44 |
| ▸ | RAB9A | P51151 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | HTT | P42858 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.40 |
| ▸ | MITF | O75030 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nifurquinazol SCHEMBL193816 | 0.84 | POLB (0.48) | KMT2AMEN1POLBNPC1RAB9A | |
| Nifurpirinol SCHEMBL1650816 | 0.79 | KMT2A (0.48) | KMT2AMEN1POLBNPC1RAB9A | |
| Nifurpirinol SCHEMBL148540 | 0.79 | KMT2A (0.48) | KMT2AMEN1POLBNPC1RAB9A | |
| Nifurquinazol SCHEMBL28266163 | 0.75 | POLB (0.40) | KMT2AMEN1POLBNPC1RAB9A | |
| Nifurquinazol SCHEMBL28121681 | 0.72 | POLB (0.37) | KMT2AMEN1POLBNPC1RAB9A | |
| SCHEMBL4887111 | 0.70 | KMT2A (0.41) | KMT2AMEN1POLBNPC1RAB9A | |
| SCHEMBL4887107 | 0.70 | KMT2A (0.41) | KMT2AMEN1POLBNPC1RAB9A | |
| SCHEMBL4882729 | 0.69 | KMT2A (0.42) | KMT2AMEN1POLBNPC1RAB9A | |
| SCHEMBL4882744 | 0.69 | KMT2A (0.42) | KMT2AMEN1POLBNPC1RAB9A | |
| SCHEMBL28433245 | 0.68 | KMT2A (0.57) | KMT2AMEN1POLBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107847505-A | MULTILAMELLAR LIPID VESICLE COMPOSITIONS AND METHODS OF USE | 威登卓制药公司 | 2018-03-27 | — | — | CN | disclosed |