Nifurquinazol

Nifurquinazol

SCHEMBL193816

O=[N+]([O-])c1ccc(-c2nc(N(CCO)CCO)c3ccccc3n2)o1

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 5/20 0.48
▸ MMP2 P08253 1/20 0.43
▸ MMP9 P14780 1/20 0.43
▸ MMP8 P22894 1/20 0.43
▸ MMP13 P45452 1/20 0.43
▸ MEN1 O00255 5/20 0.41
▸ KMT2A Q03164 5/20 0.41
▸ ALDH1A1 P00352 4/20 0.41
▸ NPSR1 Q6W5P4 4/20 0.41
▸ NPC1 O15118 4/20 0.41
▸ RAB9A P51151 3/20 0.41
▸ LMNA P02545 3/20 0.41
▸ SMN1; SMN2 Q16637 2/20 0.41
▸ RXFP1 Q9HBX9 1/20 0.41
▸ KDM4E B2RXH2 1/20 0.41
▸ MAPT P10636 5/20 0.40
▸ CYP1A2 P05177 2/20 0.40
▸ CYP3A4 P08684 2/20 0.40
▸ CYP2C9 P11712 2/20 0.40
▸ ABCG2 Q9UNQ0 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nifurquinazol SCHEMBL28266163 0.89 POLB (0.40) POLBMMP2MMP9MMP8MMP13
Nifurquinazol SCHEMBL28198699 0.84 KMT2A (0.44) POLBMMP2MMP9MMP8MMP13
Nifurquinazol SCHEMBL28121681 0.84 POLB (0.37) POLBMMP2MMP9MMP8MMP13
SCHEMBL11839731 0.81 ADORA2A (0.37) POLBMMP2MMP9MMP8MMP13
SCHEMBL11670692 0.72 POLB (0.48) POLBMEN1KMT2AALDH1A1NPSR1
SCHEMBL11881904 0.71 NSD2 (0.33) HTT
SCHEMBL11814396 0.70 MEN1 (0.65) POLBMEN1KMT2AMAPTABCG2
SCHEMBL11848448 0.70 TDP1 (0.39) MMP2MMP9MMP8MMP13ALDH1A1
SCHEMBL1083959 0.70 MAPT (0.55) POLBMEN1KMT2ANPC1RAB9A
SCHEMBL11844928 0.68 ADORA2A (0.38) POLBMMP2MMP9MMP8MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 649 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250222066-A1 COMPOSITIONS AND METHODS OF TREATING, PREVENTING OR INHIBITING A FACULTATIVE ANAEROBE INFECTION UNIVERSITY OF UTAH RESEARCH FOUNDATION 2025-07-10 — — US claimed
EP-4547023-A2 COMPOSITIONS AND METHODS OF TREATING, PREVENTING OR INHIBITING A FACULTATIVE ANAEROBE INFECTION University of Utah Research Foundation (US) 2025-05-07 — — EP claimed
WO-2024085926-A2 COMPOSITIONS AND METHODS OF TREATING, PREVENTING OR INHIBITING A FACULTATIVE ANAEROBE INFECTION UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2024-04-25 — — WO claimed
US-20220169680-A1 CELL-PENETRATING PEPTIDE BASED ON INFLUENZA VIRUS M2 PROTEIN INSTITUTE OF BASIC MEDICAL SCIENCES CHINESE ACADEMY OF MEDICAL SCIENCES (CN) 2022-06-02 — — US claimed
WO-2022040799-A1 ANTIMICROBIAL COMPOSITION GP TECH INOVASYON TEKNOLOJI VE ARASTIRMA A.S (TR) 2022-03-03 — — WO claimed
EP-3912989-A1 CELL-PENETRATING PEPTIDE BASED ON INFLUENZA VIRUS M2 PROTEIN Institute of Basic Medical Sciences Chinese Academy of Medical Sciences (CN) 2021-11-24 — — EP claimed
US-20210330645-A1 ANTIBACTERIAL COMBINATIONS MASSEY UNIVERSITY (NZ) 2021-10-28 — — US claimed
EP-3746073-A1 COMPOSITIONS FOR TREATING INFECTIVE ARTERIAL DISEASES AND RELATED CONDITIONS CENTRE FOR DIGESTIVE DISEASES (AU) 2020-12-09 — — EP claimed
US-20200276362-A1 COMPOSITION AND METHOD FOR CONTROLLED DRUG RELEASE FROM A TISSUE BARD SHANNON LIMITED (US) 2020-09-03 — — US claimed
EP-3687560-A1 COMPOSITION AND METHOD FOR CONTROLLED DRUG RELEASE FROM A TISSUE Bard Shannon Limited (PR) 2020-08-05 — — EP claimed
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 — — CN claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 — — EP claimed
EP-1931760-A2 MULTI-FUNCTIONAL IONIC LIQUID COMPOSITIONS The University of Alabama (US) 2008-06-18 — — EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 — — WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 — — US claimed
US-20070093462-A1 Multi-functional ionic liquid compositions for overcoming polymorphism and imparting improved properties for active pharmaceutical, biological, nutritional, and energetic ingredients BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA 2007-04-26 — — US claimed
WO-2007044693-A2 MULTI-FUNCTIONAL IONIC LIQUID COMPOSITIONS THE UNIVERSITY OF ALABAMA (US) 2007-04-19 — — WO claimed
EP-1578434-A2 METHODS AND COMPOSITIONS RELATING TO ISOLEUCINE BOROPROLINE COMPOUNDS Point Therapeutics, Inc. (US) 2005-09-28 — — EP claimed
US-20040077601-A1 Methods and compositions relating to isoleucine boroproline compounds POINT THERAPEUTICS, INC. 2004-04-22 — — US claimed
WO-2004004658-A2 METHODS AND COMPOSITIONS RELATING TO ISOLEUCINE BOROPROLINE COMPOUNDS POINT THERAPEUTICS, INC. (US) 2004-01-15 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070093462-A1 Multi-functional ionic liquid compositions for overcoming polymorphism and imparting improved properties for active pharmaceutical, biological, nutritional, and energetic ingredients SLC5A6, PNLIP, IPMK POLB 2061/4885MMP2 3829/4885MMP9 2798/4885
US-20200276362-A1 COMPOSITION AND METHOD FOR CONTROLLED DRUG RELEASE FROM A TISSUE PLOD3, TNNC1, S100A6 POLB 4536/4885MMP2 374/4885MMP9 849/4885
US-20040077601-A1 Methods and compositions relating to isoleucine boroproline compounds BCAT1, BCAT2, APOB POLB 369/4885MMP2 2949/4885MMP9 1698/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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