Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.58 |
| ▸ | EGFR | P00533 | 1/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.58 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.58 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | CASR | P41180 | 14/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Proxazole SCHEMBL28091109 | 1.00 | NR1I2 (0.58) | NR1I2EGFRADRA2AADORA3TBXA2R | |
| Proquazone SCHEMBL25341 | 0.76 | NR1I2 (1.00) | NR1I2EGFRADRA2AADORA3TBXA2R | |
| Proquazone SCHEMBL29508590 | 0.76 | NR1I2 (1.00) | NR1I2EGFRADRA2AADORA3TBXA2R | |
| Proxazole SCHEMBL28279739 | 0.76 | HTR1A (0.59) | ADRA2AHTR1AHRH3CYP1A2CYP2D6 | |
| Proxazole SCHEMBL24319 | 0.76 | HTR1A (0.59) | ADRA2AHTR1AHRH3CYP1A2CYP2D6 | |
| Proquazone SCHEMBL2931942 | 0.75 | NR1I2 (0.97) | NR1I2EGFRADRA2AADORA3TBXA2R | |
| Proquazone SCHEMBL11339177 | 0.73 | NR1I2 (0.79) | NR1I2EGFRADRA2AADORA3TBXA2R | |
| SCHEMBL11565990 | 0.70 | NR1I2 (0.85) | NR1I2EGFRADRA2AADORA3TBXA2R | |
| Proxazole SCHEMBL28142080 | 0.70 | HTR1A (0.52) | ADRA2AHTR1AHRH3CYP1A2CYP2D6 | |
| SCHEMBL11724593 | 0.66 | NR1I2 (0.70) | NR1I2EGFRADRA2AADORA3TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110520108-A | Compositions and methods for preventing radiation damage and promoting tissue regeneration | FIRSTSTRING RES INC | 2019-11-29 | — | — | CN | disclosed |
| CN-107847505-A | MULTILAMELLAR LIPID VESICLE COMPOSITIONS AND METHODS OF USE | 威登卓制药公司 | 2018-03-27 | — | — | CN | disclosed |