Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.97 |
| ▸ | EGFR | P00533 | 1/20 | 0.97 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.97 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.97 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.97 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.97 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.97 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.97 |
| ▸ | CASR | P41180 | 13/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Proquazone SCHEMBL25341 | 0.99 | NR1I2 (1.00) | NR1I2EGFRADRA2AADORA3TBXA2R | |
| Proquazone SCHEMBL29508590 | 0.99 | NR1I2 (1.00) | NR1I2EGFRADRA2AADORA3TBXA2R | |
| SCHEMBL11565990 | 0.91 | NR1I2 (0.85) | NR1I2EGFRADRA2AADORA3TBXA2R | |
| Proquazone SCHEMBL11339177 | 0.88 | NR1I2 (0.79) | NR1I2EGFRADRA2AADORA3TBXA2R | |
| SCHEMBL11723933 | 0.86 | NR1I2 (0.77) | NR1I2EGFRADRA2AADORA3TBXA2R | |
| Fluproquazone SCHEMBL29363976 | 0.86 | NR1I2 (0.77) | NR1I2EGFRADRA2AADORA3TBXA2R | |
| Fluproquazone SCHEMBL26210 | 0.86 | NR1I2 (0.77) | NR1I2EGFRADRA2AADORA3TBXA2R | |
| SCHEMBL11605525 | 0.85 | NR1I2 (0.76) | NR1I2EGFRADRA2AADORA3TBXA2R | |
| SCHEMBL11421197 | 0.84 | NR1I2 (0.74) | NR1I2EGFRADRA2AADORA3TBXA2R | |
| SCHEMBL7680445 | 0.83 | NR1I2 (0.72) | NR1I2EGFRADRA2AADORA3TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8939980-B2 | System for ACL reconstruction using retrograde cutter | ARTHREX, INC. (US) | 2015-01-27 | — | — | US | disclosed |
| US-20140194880-A1 | SYSTEM FOR ACL RECONSTRUCTION USING RETROGRADE CUTTER | ARTHREX, INC. (US) | 2014-07-10 | — | — | US | disclosed |
| US-8668738-B2 | Method and apparatus for ACL reconstruction using retrograde cutter | ARTHREX, INC. (US) | 2014-03-11 | — | — | US | disclosed |
| EP-1785103-B1 | Apparatus for anterior cruciate ligament (ACL) reconstruction using rotary drill cutter to form retrograde sockets | ARTHREX INC (US) | 2010-09-15 | — | — | EP | disclosed |
| US-20070233128-A1 | Method and apparatus for ACL reconstruction using retrograde cutter | ARTHREX, INC. | 2007-10-04 | — | — | US | disclosed |
| EP-1785103-A1 | Apparatus for anterior cruciate ligament (ACL) reconstruction using rotary drill cutter to form retrograde sockets | Arthrex, Inc. (US) | 2007-05-16 | — | — | EP | disclosed |