SCHEMBL28198736

SCHEMBL28198736

CC1=Cc2c(-c3cc(C(C)(C)C)cc(C(C)(C)C)c3)cccc2C1[Hf]

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
RXRB P28702 3/20 0.33
RXRA P19793 2/20 0.33
KIF11 P52732 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL17746829 0.99 RXRB (0.33) RXRBRXRA
SCHEMBL5859272 0.84 RXRB (0.34) RXRBRXRAKIF11
SCHEMBL16393905 0.83 RXRB (0.33) RXRBRXRAKIF11
SCHEMBL28050148 0.83 RXRB (0.33) RXRBRXRAKIF11
Hydrochloric Acid SCHEMBL7199635 0.82 RXRB (0.33) RXRBRXRA
Hydrochloric Acid SCHEMBL16394004 0.82 RXRB (0.33) RXRBRXRAKIF11
SCHEMBL31253543 0.82 RXRB (0.35) RXRBRXRA
Hydrochloric Acid SCHEMBL16685012 0.82 RXRB (0.33) RXRBRXRAKIF11
SCHEMBL28050155 0.81 RXRB (0.32) RXRBRXRA
SCHEMBL31099225 0.81 RXRB (0.32) RXRBRXRAKIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108026190-B Polymerization using spiral heat exchanger 埃克森美孚化学专利公司 2019-11-15 CN disclosed
CN-108026190-A Polymerization Using Spiral Heat Exchanger 埃克森美孚化学专利公司 2018-05-11 CN disclosed
CN-107683295-A Porous propylene polymer 埃克森美孚化学专利公司 2018-02-09 CN disclosed
CN-107667139-A Heterophasic copolymer and sequential polymerization 埃克森美孚化学专利公司 2018-02-06 CN disclosed