SCHEMBL28050155

SCHEMBL28050155

CC1=Cc2c(-c3cc(C(C)(C)C)cc(C(C)(C)C)c3)cccc2C1[SiH](C)C

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
RXRB P28702 3/20 0.32
RXRA P19793 2/20 0.32
RXRG P48443 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14142209 0.90
SCHEMBL29032467 0.88 HTR1A (0.38) RXRBRXRARXRG
SCHEMBL27337668 0.88 BRD4 (0.33)
SCHEMBL28878589 0.83 RXRB (0.33) RXRBRXRA
SCHEMBL29874340 0.83 RXRB (0.33) RXRBRXRA
SCHEMBL28050088 0.83 RXRA (0.30) RXRBRXRA
SCHEMBL28878599 0.83 BRD4 (0.32)
SCHEMBL28878600 0.83 BRD4 (0.32)
SCHEMBL16829542 0.82 PTGS2 (0.34)
SCHEMBL16829503 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105829326-B Bridged bis (indenyl) transition metal complexes, their preparation and use 埃克森美孚化学专利公司 2019-11-08 CN disclosed
CN-105377904-B Metallocenes and catalyst compositions derived therefrom 埃克森美孚化学专利公司 2018-07-10 CN disclosed
CN-105377904-A Metallocenes and catalyst compositions derived therefrom EXXONMOBIL CHEMICAL PATENTS INC 2016-03-02 CN disclosed
CN-105377905-A Metallocenes and catalyst compositions derived therefrom EXXONMOBIL CHEMICAL PATENTS INC 2016-03-02 CN disclosed