SCHEMBL28050148

SCHEMBL28050148

CC1=Cc2c(-c3cc(C(C)(C)C)cc(C(C)(C)C)c3)cccc2C1[SiH3]

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
RXRB P28702 3/20 0.33
RXRA P19793 2/20 0.33
KIF11 P52732 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22401709 0.87 BRD4 (0.34) KIF11
Hydrochloric Acid SCHEMBL28418788 0.84 KIF11 (0.33) KIF11
SCHEMBL5859272 0.84 RXRB (0.34) RXRBRXRAKIF11
SCHEMBL28198736 0.83 RXRB (0.33) RXRBRXRAKIF11
SCHEMBL16393905 0.83 RXRB (0.33) RXRBRXRAKIF11
SCHEMBL28326607 0.82 RXRB (0.31) RXRBRXRA
SCHEMBL28418787 0.82 BRD4 (0.32) KIF11
SCHEMBL28050147 0.82 RXRA (0.31) RXRBRXRA
Hydrochloric Acid SCHEMBL16394004 0.82 RXRB (0.33) RXRBRXRAKIF11
SCHEMBL31253543 0.82 RXRB (0.35) RXRBRXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118598726-A Preparation method of metallocene catalyst, catalyst composition and application of catalyst composition in olefin copolymerization 中化学科学技术研究有限公司 2024-09-06 CN disclosed
CN-118598726-A Preparation method of metallocene catalyst, catalyst composition and application of catalyst composition in olefin copolymerization 中化学科学技术研究有限公司 2024-09-06 CN disclosed
CN-105829326-B Bridged bis (indenyl) transition metal complexes, their preparation and use 埃克森美孚化学专利公司 2019-11-08 CN disclosed
CN-105377905-B Metallocenes and catalyst compositions derived therefrom 埃克森美孚化学专利公司 2018-09-14 CN disclosed
CN-105377904-B Metallocenes and catalyst compositions derived therefrom 埃克森美孚化学专利公司 2018-07-10 CN disclosed
CN-105829326-A Bridged bis (indenyl) transition metal complexes, their preparation and use 埃克森美孚化学专利公司 2016-08-03 CN disclosed
CN-105377904-A Metallocenes and catalyst compositions derived therefrom EXXONMOBIL CHEMICAL PATENTS INC 2016-03-02 CN disclosed
CN-105377905-A Metallocenes and catalyst compositions derived therefrom EXXONMOBIL CHEMICAL PATENTS INC 2016-03-02 CN disclosed