Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 19/20 | 0.85 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.85 |
| ▸ | HTR2B | P41595 | 1/20 | 0.85 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.85 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15942032 | 0.92 | GRM4 (1.00) | GRM4KCNH2HTR2BMTNR1A | |
| SCHEMBL7859091 | 0.82 | GRM4 (1.00) | GRM4KCNH2HTR2BMTNR1A | |
| SCHEMBL2710540 | 0.81 | GRM4 (0.77) | GRM4KCNH2HTR2BMTNR1AGRM2 | |
| SCHEMBL18292374 | 0.79 | GRM4 (0.74) | GRM4KCNH2HTR2BMTNR1A | |
| SCHEMBL17125376 | 0.75 | GRM4 (0.67) | GRM4KCNH2HTR2BMTNR1A | |
| SCHEMBL18247351 | 0.73 | GRM4 (0.58) | GRM4KCNH2HTR2BMTNR1AGRM2 | |
| SCHEMBL355762 | 0.73 | GRM4 (0.65) | GRM4KCNH2HTR2BMTNR1AGRM2 | |
| SCHEMBL31428975 | 0.73 | GRM4 (0.65) | GRM4KCNH2HTR2BMTNR1AGRM2 | |
| SCHEMBL100305 | 0.72 | GRM4 (1.00) | GRM4KCNH2HTR2BMTNR1A | |
| SCHEMBL28311465 | 0.71 | AURKA (0.50) | GRM4KCNH2HTR2BMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108473962-A | Reproducible differentiation method of clinical grade retinal pigment epithelial cells | (由卫生与公众服务部部长代表的)美利坚合众国 | 2018-08-31 | — | — | CN | claimed |
| CN-109890956-A | The preparation method of people's liver precursor | 国立研究开发法人国立癌研究中心 | 2019-06-14 | — | — | CN | disclosed |
| CN-109312306-A | The method for generating retinal tissue | 大日本住友制药株式会社 | 2019-02-05 | — | — | CN | disclosed |
| CN-109153970-A | Endothelial cell derived from human stem cells, endothelium-liver cell co-culture system with and application thereof | 新加坡科技研究局 | 2019-01-04 | — | — | CN | disclosed |
| CN-108934168-A | For non-pluripotent cell to be reprogrammed to the improved method for multipotential stem cell | 北昊干细胞与再生医学研究院有限公司 | 2018-12-04 | — | — | CN | disclosed |
| CN-108473962-A | Reproducible differentiation method of clinical grade retinal pigment epithelial cells | (由卫生与公众服务部部长代表的)美利坚合众国 | 2018-08-31 | — | — | CN | disclosed |
| CN-108291206-A | MACS-based purification of stem cell-derived retinal pigment epithelium | 富士胶片细胞动力公司 | 2018-07-17 | — | — | CN | disclosed |
| CN-107636149-A | EX VIVO PROLIFERATION OF EPITHELIAL CELLS | 普罗帕格尼克斯公司 | 2018-01-26 | — | — | CN | disclosed |