Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 12/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.58 |
| ▸ | HTR2B | P41595 | 1/20 | 0.58 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.58 |
| ▸ | BMP4 | P12644 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | TTK | P33981 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31428975 | 0.76 | GRM4 (0.65) | GRM4KCNH2HTR2BMTNR1ABMP4 | |
| SCHEMBL355762 | 0.76 | GRM4 (0.65) | GRM4KCNH2HTR2BMTNR1ABMP4 | |
| SCHEMBL28863738 | 0.75 | TGFBR1 (0.51) | GRM4KCNH2HTR2BMTNR1ABMP4 | |
| SCHEMBL15942032 | 0.73 | GRM4 (1.00) | GRM4KCNH2HTR2BMTNR1A | |
| SCHEMBL28199101 | 0.73 | GRM4 (0.85) | GRM4KCNH2HTR2BMTNR1AGRM2 | |
| SCHEMBL7859091 | 0.69 | GRM4 (1.00) | GRM4KCNH2HTR2BMTNR1A | |
| SCHEMBL35327 | 0.69 | TGFBR1 (0.60) | GRM4KCNH2HTR2BMTNR1ABMP4 | |
| SCHEMBL30439957 | 0.69 | TGFBR1 (0.60) | GRM4KCNH2HTR2BMTNR1ABMP4 | |
| SCHEMBL2710540 | 0.69 | GRM4 (0.77) | GRM4KCNH2HTR2BMTNR1AGRM2 | |
| SCHEMBL28019346 | 0.68 | TGFBR1 (0.60) | GRM4KCNH2HTR2BMTNR1ABMP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109996870-A | Midbrain specificity organoid is generated from human pluripotent stem cells | 新加坡科技研究局 | 2019-07-09 | — | — | CN | disclosed |
| WO-2016187135-A1 | EPIDERMAL NEURAL CREST STEM CELLS AS A SOURCE OF SCHWANN CELLS | SIEBER-BLUM MAYA (US) | 2016-11-24 | — | — | WO | disclosed |