Diphenylmethane

Diphenylmethane

SCHEMBL28199244

N=C=S.c1ccc(Cc2ccccc2)cc1

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.67
MIF P14174 3/20 0.46
TRPA1 O75762 2/20 0.46
ALDH1A1 P00352 1/20 0.46
CYP3A4 P08684 1/20 0.46
HPGD P15428 1/20 0.46
LTA4H P09960 1/20 0.44
MAOB P27338 1/20 0.43
IDH1 O75874 1/20 0.43
CYP2E1 P05181 1/20 0.43
CYP2A6 P11509 1/20 0.43
HIF1A Q16665 1/20 0.43
CYP2A13 Q16696 1/20 0.43
EPAS1 Q99814 1/20 0.43
PRSS1 P07477 1/20 0.42
PRSS2 P07478 1/20 0.42
PRSS3 P35030 1/20 0.42
PLA2G10 O15496 1/20 0.41
PLA2G2A P14555 1/20 0.41
LMNA P02545 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylmethane SCHEMBL10593337 1.00 CALM1 (0.67) CALM1MIFTRPA1ALDH1A1CYP3A4
Diphenylmethane SCHEMBL5433494 0.88 CALM1 (0.75) CALM1TRPA1ALDH1A1CYP3A4LTA4H
Diphenylmethane SCHEMBL5591702 0.88 CALM1 (0.75) CALM1TRPA1ALDH1A1CYP3A4LTA4H
Diphenylmethane SCHEMBL333766 0.83 CALM1 (0.67) CALM1CYP3A4LTA4HMAOBIDH1
Diphenylmethane SCHEMBL28457396 0.83 CALM1 (0.67) CALM1CYP3A4LTA4HMAOBIDH1
Diphenylmethane SCHEMBL9449990 0.83 CALM1 (0.67) CALM1CYP3A4LTA4HMAOBIDH1
Diphenylmethane SCHEMBL7497963 0.83 CALM1 (0.67) CALM1CYP3A4LTA4HMAOBIDH1
Diphenylmethane SCHEMBL465158 0.83 CALM1 (0.67) CALM1CYP3A4LTA4HMAOBIDH1
Diphenylmethane SCHEMBL15415 0.83 CALM1 (0.67) CALM1CYP3A4LTA4HMAOBIDH1
Diphenylmethane SCHEMBL28763356 0.83 CALM1 (0.67) CALM1CYP3A4LTA4HMAOBIDH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113929866-B Modified resin and resin composition 旭化成株式会社 2023-07-07 CN disclosed
CN-111205424-B Modified resin and resin composition 旭化成株式会社 2022-04-08 CN disclosed
CN-113929866-A Modified resin and resin composition 旭化成株式会社 2022-01-14 CN disclosed
CN-107629183-B Modified resin and resin composition 旭化成株式会社 2021-01-05 CN disclosed
CN-111205424-A Modified resin and resin composition 旭化成株式会社 2020-05-29 CN disclosed
CN-105358602-B modified resin and resin composition 旭化成株式会社 2018-12-04 CN disclosed
CN-107629183-A Modified resin and resin combination 旭化成株式会社 2018-01-26 CN disclosed