Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.55 |
| ▸ | PLAU | P00749 | 1/20 | 0.55 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.55 |
| ▸ | ELANE | P08246 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28113504 | 0.82 | F2 (0.40) | F2PLAUKLKB1ELANEKMT2A | |
| SCHEMBL5531898 | 0.80 | SMN1; SMN2 (0.58) | F2PLAUKLKB1ELANEKMT2A | |
| SCHEMBL24937400 | 0.79 | L3MBTL1 (0.56) | F2PLAUKLKB1ELANEKMT2A | |
| SCHEMBL18704008 | 0.78 | F2 (0.50) | F2PLAUKLKB1ELANEKMT2A | |
| SCHEMBL883182 | 0.78 | F2 (0.50) | F2PLAUKLKB1ELANEKMT2A | |
| SCHEMBL14699330 | 0.77 | — | — | |
| SCHEMBL28308404 | 0.77 | — | — | |
| SCHEMBL27988980 | 0.77 | — | — | |
| SCHEMBL17437902 | 0.77 | F2 (0.46) | F2PLAUKLKB1ELANEKMT2A | |
| SCHEMBL7056151 | 0.76 | F2 (0.48) | F2PLAUKLKB1ELANEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105555780-B | SYK inhibitors | 吉利德科学公司 | 2018-01-23 | — | — | CN | disclosed |