Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.59 |
| ▸ | ACHE | P22303 | 1/20 | 0.59 |
| ▸ | MAOA | P21397 | 3/20 | 0.56 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.54 |
| ▸ | CDK1 | P06493 | 1/20 | 0.54 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.54 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.54 |
| ▸ | CDK2 | P24941 | 1/20 | 0.54 |
| ▸ | GSK3B | P49841 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | KDM5A | P29375 | 1/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | EDNRA | P25101 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MGAM | O43451 | 2/20 | 0.49 |
| ▸ | FASN | P49327 | 1/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4914778 | 0.87 | MAOA (0.61) | BCHEACHEMAOAESR1KDM5A | |
| SCHEMBL16527515 | 0.86 | MAOB (0.50) | BCHEACHEMAOAESR1KDM5A | |
| SCHEMBL19774090 | 0.85 | EDNRA (0.49) | BCHEACHEMAOAESR1KDM5A | |
| SCHEMBL29853607 | 0.82 | ACHE (0.59) | BCHEACHECCNE2CDK1CCNB1 | |
| SCHEMBL29167450 | 0.78 | KDM4E (0.56) | MAOACCNE2CDK1CCNB1CCNE1 | |
| SCHEMBL7546749 | 0.76 | BCHE (0.60) | BCHEACHEMAOAMAOBEDNRA | |
| SCHEMBL27651725 | 0.76 | MEN1 (0.60) | BCHEACHEMAOAMAOBEDNRA | |
| SCHEMBL30786764 | 0.75 | MAOA (0.71) | MAOAESR1KDM5AESR2MGAM | |
| SCHEMBL1230282 | 0.75 | MAOA (0.71) | MAOAESR1KDM5AESR2MGAM | |
| SCHEMBL30711777 | 0.75 | MAOA (0.71) | MAOAESR1KDM5AESR2MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104557892-B | A kind of mangiferin unit point derivative and its production and use | 北京大学 | 2018-01-02 | — | — | CN | disclosed |